The way that this Covid vaccine works is quite different from the flu shot. The Covid vax. is not a (dead) bacteria or virus being injected into your body. (With Pfizer & Moderna) RNA (called messenger RNA) that's been coded in a lab goes into your arm. The RNA has instructions, or a code, that gets deposited on the cell. The ribosomes of the cell make a spike protein. It looks similar to the spike protein on the surface of the actual Corona virus. Then your body is supposed to make antibodies (antigens) that goes after the spike protein and neutralize it.
The problem is that this has not been tested in any long-term studies, so, this is more of an experiment. We don't know whether or not the DNA gets permanently changed (possibly bad). We're talking about something that's not supposed to be in your body (made in a lab) that can bind to the surface of your cells and possibly may not be able to be reversed.
Also, since the drug is still being evaluated for long term adverse effects, pregnancy, etc., the FDA would not license the drug, but instead, put out as EUA... Emergency Use Authorization.
at present, there is nodirect evidence (from studies on COVID-19) on the effectiveness facemasking of healthy people in the community to prevent infection ofrespiratory viruses, including COVID-19
”
[2]. Despite these contro-versies, the potential harms and risks of wearing facemasks were clearlyacknowledged. These including self-contamination due to hand practiceor non-replaced when the mask is wet, soiled or damaged, developmentof facial skin lesions, irritant dermatitis or worsening acne and psy-chological discomfort. Vulnerable populations such as people withmental health disorders, developmental disabilities, hearing problems,those living in hot and humid environments, children and patients withrespiratory conditions are at signicant health risk for complicationsand harm[2].
Physiological effects of wearing facemasks
Wearing facemask mechanically restricts breathing by increasing theresistance of air movement during both inhalation and exhalation pro-cess[12,13]. Although, intermittent (several times a week) and repeti-tive (10
–
15 breaths for 2
–
4 sets) increase in respiration resistance maybe adaptive for strengthening respiratory muscles[33,34], prolongedand continues effect of wearing facemask is maladaptive and could bedetrimental for health[11
–
13]. In normal conditions at the sea level, aircontains 20.93% O
2
and 0.03% CO
2
, providing partial pressures of 100mmHg and 40 mmHg for these gases in the arterial blood, respectively.These gas concentrations signicantly altered when breathing occursthrough facemask. A trapped air remaining between the mouth, noseand the facemask is rebreathed repeatedly in and out of the body, con-taining low O
13,35,36]. Severe hypoxemia may also provoke car-diopulmonary and neurological complications and is considered animportant clinical sign in cardiopulmonary medicine[37
–
42]. Low ox-ygen content in the arterial blood can cause myocardial ischemia,serious arrhythmias, right or left ventricular dysfunction, dizziness,hypotension, syncope and pulmonary hypertension[43]. Chronic low-grade hypoxemia and hypercapnia as result of using facemask cancause exacerbation of existing cardiopulmonary, metabolic, vascularand neurological conditions[37
–
42].Table 1summarizes the physio-logical, psychological effects of wearing facemask and their potentiallong-term consequences for health.In addition to hypoxia and hypercapnia, breathing through facemaskresidues bacterial and germs components on the inner and outside layerof the facemask. These toxic components are repeatedly rebreathed backinto the body, causing self-contamination. Breathing through facemasksalso increases temperature and humidity in the space between themouth and the mask, resulting a release of toxic particles from themask
’
s materials[1,2,19,26,35,36]. A systematic literature reviewestimated that aerosol contamination levels of facemasks including 13 to202,549 different viruses[1]. Rebreathing contaminated air with highbacterial and toxic particle concentrations along with low O
2
and highCO
2
levels continuously challenge the body homeostasis, causing self-toxicity and immunosuppression[1,2,19,26,35,36].A study on 39 patients with renal disease found that wearing N95facemask during hemodialysis signicantly reduced arterial partial ox-ygen pressure (from PaO
2
101.7 to 92.7 mm Hg), increased respiratoryrate (from 16.8 to 18.8 breaths/min), and increased the occurrence ofchest discomfort and respiratory distress[35]. Respiratory ProtectionStandards from Occupational Safety and Health Administration, USDepartment of Labor states that breathing air with O
2
concentrationbelow 19.5% is considered oxygen-deciency, causing physiological andhealth adverse effects. These include increased breathing frequency,accelerated heartrate and cognitive impairments related to thinking andcoordination[36]. A chronic state of mild hypoxia and hypercapnia hasbeen shown as primarily mechanism for developing cognitive dysfunc-tion based on animal studies and studies in patients with chronicobstructive pulmonary disease[44].The adverse physiological effects were conrmed in a study of 53surgeons where surgical facemask were used during a major operation.After 60 min of facemask wearing the oxygen saturation dropped bymore than 1% and heart rate increased by approximately ve beats/min[45]. Another study among 158 health-care workers using protectivepersonal equipment primarily N95 facemasks reported that 81% (128workers) developed new headaches during their work shifts as thesebecome mandatory due to COVID-19 outbreak. For those who used theN95 facemask greater than 4 h per day, the likelihood for developing aheadache during the work shift was approximately four times higher[Odds ratio
=
3.91, 95% CI (1.35
–
11.31) p
=
0.012], while 82.2% of theN95 wearers developed the headache already within
≤
10 to 50 min[46].With respect to cloth facemask, a RCT using four weeks follow upcompared the effect of cloth facemask to medical masks and to no maskson the incidence of clinical respiratory illness, inuenza-like illness andlaboratory-conrmed respiratory virus infections among 1607 partici-pants from 14 hospitals[19]. The results showed that there were nodifference between wearing cloth masks, medical masks and no masksfor incidence of clinical respiratory illness and laboratory-conrmedrespiratory virus infections. However, a large harmful effect withmore than 13 times higher risk [Relative Risk
=
13.25 95% CI (1.74 to100.97) was observed for inuenza-like illness among those who werewearing cloth masks[19].
This "study" has nothing to do with the NIH and is filled with bullcrap. As someone who wore masks all day-every day at work (even for 24 hour shifts), I never became hypercapneic, hypoxic or developed a mask headache. I never became depressed or socially isolated because other colleagues were wearing masks. We didn't re-use masks on different cases and we changed wet masks (downright uncomfortable) so subjects wearing masks in this condition shouldn't even be mentioned. Where do you come up with these studies that are so obviously flawed that they are comically awful? Please just eliminate studies with .com attached to them and stick to Google Scholar. Do you even know about Google Scholar?
Specializes in Physiology, CM, consulting, nsg edu, LNC, COB.
1 hour ago, GrumpyRN said:
"...given the fact that facemasks restrict breathing, causing hypoxemia and hypercapnia and increase the risk for respiratory complications, self-contamination and exacerbation of existing chronic conditions..."
Yeah, you tell that to your surgeon before he starts surgery. And anesthesia, scrub techs, and circulating RNs. No masks for a couple of hours, no problem. (I know Grumpy didn’t list this originally but can’t figure out how to change that, sorry)
NCBI is an online library of anything remotely health related, including non-peer reviewed journals like "Medical Hypotheses". Suggesting that an article is the product of, or endorsed by the NIH because it can be found in NCBI is a bit like saying because The Hobbit can be found in Harvard libraries, that Harvard is confirming the existence of Middle Earth.
And I don't think there's much argument that we should make sure we understand any detrimental effects of mask wearing, including if they cause things like chronic hypoxia, which is why it's been well studied and no evidence has been found that it does.
You know what does cause life-threatening hypoxia however, Covid.
It specifically states :- "The paper was published by an exercise physiologist with no academic connection to Stanford University or the NIH in a journal that accepts "radical, speculative and non-mainstream scientific ideas."
It specifically states :- "The paper was published by an exercise physiologist with no academic connection to Stanford University or the NIH in a journal that accepts "radical, speculative and non-mainstream scientific ideas."
Sort of similar to the non working fired radiologist Trump hired as the expert Covid crisis? At least he supposedly knew more than kushner?
Parents have all the vids of all the shows from Last of the Summer to Morcombe and Wise. We grew up on those vids.
Sorry, I know this is late and off topic but...
Have you seen Red Dwarf? Very funny and cult viewing now. Started in 1980's and released a feature length film last year. Has released a series or show in every decade since the 1980's.
Have you seen Red Dwarf? Very funny and cult viewing now. Started in 1980's and released a feature length film last year. Has released a series or show in every decade since the 1980's.
Amen. My husband had a guy at his work respond back to their credentials nurse that he refused to get the vaccine because “it altered human DNA”-he sent this back as a reply all so it went to the whole company with some more flowery words I cannot use here. SMH. Misinformation will be the hardest thing to combat regarding stomping out this damn virus if people keep thinking crazy talk.
In the US, we have not actually had "lockdowns," though that term is thrown around constantly. No one has kept me from going anywhere I like. Many of us voluntarily stayed home much more than normal to reduce our potential exposure to other people. Many of us were directed to work from home in order to minimize exposure/spread of the virus. Certain businesses were closed for a period of time.
But I know of no forced lockdowns where we could not leave our homes or could only leave them to go to the grocery store or to seek medical care in the US.
As for being treated like "lab rats", give me a break. Lab rats have no say in what happens to them. No competent adult in the US has been forced to endure an experimental treatment against their will during this pandemic.
And I don't think there's much argument that we should make sure we understand any detrimental effects of mask wearing, including if they cause things like chronic hypoxia, which is why it's been well studied and no evidence has been found that it does.
You know what does cause life-threatening hypoxia however, Covid.
Exactly. Think of all the doctors, nurses, etc., who should be dropping like flies if this were true. Staff in ORs, procedure rooms, infectious disease units, organ and bone marrow transplant units, cancer units, etc. all over the world would be in terrible shape. Of course, that's not the case.
I have worked OR for years. No one has EVER demanded I remove my mask or called me names for wearing it. Every single one of my patients seemed to understand that the masks DO IN FACT PROTECT THEM from any infected droplets I might be spewing into the room. But because a certain politician declined to mask up, people suddenly have all these expert opinions that not only do masks not work, they can kill!
In the US, we have not actually had "lockdowns," though that term is thrown around constantly. No one has kept me from going anywhere I like. Many of us voluntarily stayed home much more than normal to reduce our potential exposure to other people. Many of us were directed to work from home in order to minimize exposure/spread of the virus. Certain businesses were closed for a period of time.
But I know of no forced lockdowns where we could not leave our homes or could only leave them to go to the grocery store or to seek medical care in the US.
As for being treated like "lab rats", give me a break. Lab rats have no say in what happens to them. No competent adult in the US has been forced to endure an experimental treatment against their will during this pandemic.
Early on in the pandemic when we were mostly closed down, we were ENCOURAGED to get outside for daily exercise. Outdoor exercise has consistently been encoured during this entire time. No one was ever "Locked" in their house. Silly.
mdcp
60 Posts
NCBI is under the NIH!