Does the shot mess with your DNA?

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The way that this Covid vaccine works is quite different from the flu shot. The Covid vax. is not a (dead) bacteria or virus being injected into your body. (With Pfizer & Moderna) RNA (called messenger RNA) that's been coded in a lab goes into your arm. The RNA has instructions, or a code, that gets deposited on the cell. The ribosomes of the cell make a spike protein. It looks similar to the spike protein on the surface of the actual Corona virus. Then your body is supposed to make antibodies (antigens) that goes after the spike protein and neutralize it. 

The problem is that this has not been tested in any long-term studies, so, this is more of an experiment. We don't know whether or not the DNA gets permanently changed (possibly bad). We're talking about something that's not supposed to be in your body (made in a lab) that can bind to the surface of your cells and possibly may not be able to be reversed. 

Also, since the drug is still being evaluated for long term adverse effects, pregnancy, etc., the FDA would not license the drug, but instead, put out as EUA... Emergency Use Authorization.

Rose_Queen, BSN, MSN, RN

6 Articles; 11,265 Posts

Specializes in OR, Nursing Professional Development. Has 18 years experience.

the mRNA does not enter the nucleus of the cell, therefore it cannot change DNA.

https://www.CDC.gov/vaccines/covid-19/hcp/mrna-vaccine-basics.html

Quote

After the piece of the spike protein is made, the cell breaks down the mRNA strand and disposes of them using enzymes in the cell. It is important to note that the mRNA strand never enters the cell’s nucleus or affects genetic material. This information helps counter misinformation about how mRNA vaccines alter or modify someone’s genetic makeup.

 

Soloist, LPN

72 Posts

Having a decent understanding of cellular biology really helps understand this. One thing to study or to read up on is the Chinese researcher who went to jail for editing embryos... https://www.nature.com/articles/d41586-019-00673-1 and read this comparing two types of cellular genetic modifications.

If you dig a little into this you come across and idea of the cells having some with mutations and some without resulting in more problems (mosaic). This is due to the timing of the edit in early embryology.

Assuming the Government and the manufacturers and a whole lot of other people lied to us, the only way this could actually cause localized changes to cells or specifically 1 type of cells would be if they had a reverse transcriptase with the vaccine. Otherwise... the RNA does nothing to your genetic code.  

This is a great link to explain some of what you actually can do with genetic editing

https://www.ncbi.nlm.nih.gov/books/NBK447276/

macawake, MSN

2,141 Posts

Has 15 years experience.
17 hours ago, Floor_Nurse said:

Does the vaccine mess with your DNA? 
The way that this Covid vaccine works is quite different from the flu shot. The Covid vax. is not a (dead) bacteria or virus being injected into your body. (With Pfizer & Moderna) RNA (called messenger RNA) that's been coded in a lab goes into your arm. The RNA has instructions, or a code, that gets deposited on the cell. The ribosomes of the cell make a spike protein. It looks similar to the spike protein on the surface of the actual Corona virus. Then your body is supposed to make antibodies (antigens) that goes after the spike protein and neutralize it. 

The problem is that this has not been tested in any long-term studies, so, this is more of an experiment. We don't know whether or not the DNA gets permanently changed (possibly bad). We're talking about something that's not supposed to be in your body (made in a lab) that can bind to the surface of your cells and possibly may not be able to be reversed. 

Also, since the drug is still being evaluated for long term adverse effects, pregnancy, etc., the FDA would not license the drug, but instead, put out as EUA... Emergency Use Authorization.

I’m far too tired to write a long answer, but the short answer is NO, mRNA vaccines do NOT alter or interact with the cell nucleus. It will NOT change  your, my or anyone else’s DNA. So we DO indeed know that our DNA doesn’t get permanently, or even temporarily, changed. 

As a nurse I’m sure you are aware that a virus invades and hijacks the machinery of the host’s cells in order to replicate (the host would be you, I or anyone else who gets infected by a virus like for example SARS-CoV-2). 

To me that’s a lot more scary than a vaccine. 

Here are some resources to read more about what happens when you get infected by a virus and how they get hard to work INSIDE of your cells...

https://medicine.yale.edu/coved/modules/virus/hijacking/

https://www.ncbi.nlm.nih.gov/books/NBK8181/

https://www.immunology.org/public-information/bitesized-immunology/pathogens-and-disease/virus-replication

and one final link about genetic engineering.. 

https://allianceforscience.cornell.edu/blog/2020/12/yes-some-covid-vaccines-use-genetic-engineering-get-over-it/

Hlopez90

18 Posts

I still can’t believe some nurses believe this... Yikes. The vaccine DOES NOT go into any of your cells, it’s there to create an immune response for your own cells so that they can detect the virus in future infections via the spike proteins the virus presents. Spike proteins are part of the virus that attach to the cells, the virus capsule itself is what has the “DNA” (instructions) which actually goes into the cell via “injection” to hijack and take over the to replicate and infect. 

Jack Peace

97 Posts

Whether or not the vaccine mRNA enters your cells is irrelevant. The fact that these types of vaccines have never publicly been tested on humans is a concern that many of us have with the long term unknowns of this. People have a right to be skeptical especially when it concerns one's health. Because, you know, we are in healthcare. 

LovingLife123

1,577 Posts

1 minute ago, Jack Peace said:

Whether or not the vaccine mRNA enters your cells is irrelevant. The fact that these types of vaccines have never publicly been tested on humans is a concern that many of us have with the long term unknowns of this. People have a right to be skeptical especially when it concerns one's health. Because, you know, we are in healthcare. 

Sigh.  Yes, it has been tested.  I’m flabbergasted every time I come to this site anymore.  I thought we all took Microbiology for our degrees.  Do we actually have nurses with a degree in science not understanding DNA, RNA, and how immune systems and vaccines work?

They did testing.  One of the bigger testing happening in my own state.  The reason this vaccine came to market sooner than most was when production was allowed to begin. That was the difference.  Stop acting like this is a mysterious drug that just randomly showed up.  Thousands of people volunteered to be test subjects.  

Shelby91

28 Posts

Specializes in med surg.

Unfortunately, like many medications produced in the past, adverse long term effects are not discovered until years later. There's no way to know for sure that this vaccine or any other new drug is safe in the long run until we see the outcome in the future. Hopefully this will be the miracle cure that'll stop the pandemic; as for myself, I'm going to go with my gut instinct and use the watch and see approach. With that said, I'd like to also add that I don't pass judgement on people that decide to get it or not, it truly is a personal choice.

Hlopez90

18 Posts

It’s not really a personal choice when you’re a healthcare worker in my opinion. It’s not just about you, it’s about the community you work with. I’ve had both doses and absolutely no symptoms except a light fever and some fatigue that same day (normal, it’s an immune response- body is doing its job). Every medicine you take has the possibility to cause reaction, it’s just how probability works.  I guess I can say that I’m grateful in hindsight that I had a virology researcher as my Microbiology teacher, no matter how difficult she made the class, she broke everything down; it’s so relevant today and helped me personally tell shady info from real info. The reason it took so little time is because governments and companies cut the red tape that usually causes so much time in between  vaccine research, development, and release. Literally 1000s of researchers and scientists teamed up around the world and used shared platforms to share information and work together; I don’t think some of you realize how historic this is. Also, 1000s of human participants courageously volunteered as testing subjects. I’m not judging anyone but a simple Google search (obviously looking at legit articles) will produce this information for anyone. 

56 minutes ago, Jack Peace said:
56 minutes ago, Jack Peace said:

Yea 2 month testing that's it. No long term testing. Skipped animal trials also. 

http://www.physiciansforlife.org/bill-gates-father-head-of-planned-parenthood-inspired-his-abortion-population-control-views/

Citing conspiracy theory material are we now? Yikes...

toomuchbaloney

9,748 Posts

Specializes in NICU, PICU, Transport, L&D, Hospice. Has 44 years experience.

It's not clear, @Hlopez90 that all commenting are health professionals.