Why do you give IV nexium and protonix slow?!

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K guys, I've looked high and low for this answer and I have even asked 3 pharmacists about this and two house supervisors and NO ONE seems to know why we give nexium and protonix over 3 and 15 minutes respectively. It's just bugging me to know end. If I'm going to be doing something I tend to want to know what the evidence is behind it. So if anyone knows why we give IV nexium and IV protonix over slow rates please help me out :-D

Craig

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Specializes in Acute Care Cardiac, Education, Prof Practice.

I am currently searching through research, however I have always given it slow to prevent my patient from suddenly vomiting. I can not at this moment find the pharmacodynamics of why this happens.

Tait

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Specializes in Emergency.

Hi,

The only thing I can come up with (and we give it over 15 minutes too) is that there can be anaphylaxis and thrombophlebitis when given IV. Also other injection site reactions, so you give it slow to ensure a patent vein, and hyperglycemia and vertigo.

Hope this helps.

Amy

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Specializes in ER.

Our references say 2 minutes for Protonix.

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Specializes in Neuro ICU and Med Surg.

Our reference says 2-3 minutes for protonix.

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Specializes in Vascular Access.
K guys, I've looked high and low for this answer and I have even asked 3 pharmacists about this and two house supervisors and NO ONE seems to know why we give nexium and protonix over 3 and 15 minutes respectively. It's just bugging me to know end. If I'm going to be doing something I tend to want to know what the evidence is behind it. So if anyone knows why we give IV nexium and IV protonix over slow rates please help me out :-D

Craig

Every medication has a certain amount of mg or micrograms to be given over a certain time frame and one should follow those time frames namely to prevent SPEED SHOCK. If a medication is given faster than recommended, it can cause facial flushing, headaches, hypotension, rapid, thready pulse, dyspnea, and even cardiac arrest.

There is only one medication that I know of which can be given, and should be given over 2-3 seconds and that is Adenosine for SVT.

So, follow manufacturers recommendations please.

:mad:

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Specializes in SRNA.
Our references say 2 minutes for Protonix.

This is how fast I've been giving it for the past year...

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Specializes in cardiac.

I've never given Protonix over 15 minutes. Two minutes and have never had a problem.

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Specializes in critical care; hospice.

same..never had a prob with time on IV protonix!

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We give all of our protonix IV in piggyback bags to be run over 30 minutes. Nexium isn't given at our hospital but where I did many of my student clinicals, it was the drug of choice and we gave it over 5 minutes with our instructors.

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Specializes in Med Surg, ER, OR.

Yeah the references here state to push over 2-3 minutes. I usually give it in about 1-2 and am just fine. But definitely if you give these meds quickly (especially zofran, reglan) it can quickly cause N/V

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