The first time I applied to nursing school (about 5-6 years ago), I only applied to the school that I was already attending. Was wait listed and ended up completing a BS in a different area instead of continuing to pursue nursing. When I decided to go back to school, I only applied to one program and was accepted right away.
So if possible, do as I say and not as I do.
The second time around, I really wasn't in a position to relocate for school. I also wasn't willing to pay $60,000+ to attend the other program in my area. If you are able to apply to more than one school, I would definitely recommend it. The admissions process is much less stressful when you have back-ups.