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Early Studies Show Remdesivir Improves COVID-19 Mortality Rates

Posted

Specializes in Peds, Med-Surg, Disaster Nsg, Parish Nsg.

Dr. Anthony Fauci says there is clear-cut evidence that Remdesivir works. In an early clinical study, patients had a lower mortality rate when treated with Remdesivir compared to those treated with a placebo. Remdesivir was shown to decrease the average recovery rate from 15 days to 11 days.

Remdesivir can block an enzyme used by the Coronavirus and therefore blocking the effects of the virus.

This will be a new standard of care.

HiddenAngels

Has 7 years experience.

Fingers crossed

Gilead is well known for profiteering in the pharmaceutical industry.

That will be fantastic, if it really works. It's so hard seeing these sick patients and not knowing what meds will help them.

We have used Kaletra (lopinavir and ritonavir) with some of our COVID+ patients. I'm not sure if our hospital was part of a study or just our ID doctors trying something that looked promising, but for a while we were giving everyone Kaletra and Plaquenil (if their QTC was okay), and then we just kinda stopped. Now we're giving IV ascorbic acid.

I will be over the moon happy if we can have something that really works. Especially if we pair this with an early catch through expanded testing, an effective antiviral might be able to nip some infections in the bud.

tnbutterfly - Mary, BSN, RN

Specializes in Peds, Med-Surg, Disaster Nsg, Parish Nsg.

Remdesivir has not been approved by the FDA for treatment of anything, however, an emergency FDA authorization is expected as soon as today.

We’re using at our hospital and have not had as encouraging results but I’m sure there are other factors involved. Almost all of our patients are from congregate living situations.

Marisette, BSN, RN

Specializes in Registered Nurse. Has 28 years experience.

I suspect this medication is being used on the very sick. Perhaps sooner treatment with Remdesivir would lead to better outcomes. How readily available will this medication be if approved by FDA ?

tnbutterfly - Mary, BSN, RN

Specializes in Peds, Med-Surg, Disaster Nsg, Parish Nsg.

UPDATE

The FDA has just authorized emergency use to treat coronavirus.

Gilead, the company producing Remdesivir, will be donating 1 million vials of the drug.

18 minutes ago, tnbutterfly - Mary said:

UPDATE

The FDA has just authorized emergency use to treat coronavirus.

Gilead, the company producing Remdesivir, will be donating 1 million vials of the drug.

Applause to Gilead because had this been that CEO who price gouged Epipen we would have been in deep trouble!

InTheLongRun

Has 15 years experience.

5 hours ago, tnbutterfly - Mary said:

UPDATE

The FDA has just authorized emergency use to treat coronavirus.

Gilead, the company producing Remdesivir, will be donating 1 million vials of the drug.

I'd be curious to know how many doses for Corvid tx that equates to.

Anyone?

hh.bsn.rn.ccrn, BSN, RN

Specializes in Coronary Care/Cardiovascular ICU. Has 13 years experience.

1 hour ago, InTheLongRun said:

I'd be curious to know how many doses for Corvid tx that equates to.

Anyone?

Just read in a NY Times article that Gilead stated 1.5 million vials would treat 150,000 patients.

We're already using it (part of the trial) and I'm quite impressed.

33 minutes ago, sevensonnets said:

We're already using it (part of the trial) and I'm quite impressed.

What are you seeing, in terms of pre and post-trial symptoms/treatment?