Covid-19 Vaccine Trials in South Africa: Another Tuskegee? #Black Lives Matter Around the World

Black this….., black that……, poverty this …, health disparities that….., police brutality here and am adding to the list, black exploitation by pharmaceuticals. Why not test in Italy, France, New York, New Jersey or Connecticut? Racism? Bigotry? Greediness? Ignorance or Plain Stupidity #Black Lives Matter around the world.

Updated:  

The death of George Floyd has unveiled many atrocities done to harm black people all over the world. We have seen all races united to give us a voice. During COVID-19, poverty, health disparities and comorbidities such as HTN and diabetes have claimed the lives of black people more than other races. Black people have been hit by a double edged sword, everywhere they turn, they are being exploited, killed or harmed and pharmaceuticals are guilty as well, they see black poor people, they see gold, they test medications, vaccines and perform medical trials, yet black people do not reap what these companies harvest: they do not enjoy the proceeds, yet remain poor, die from harm or plain simple, contribute without enough compensation

Amid all the riots and chaos in the world, I was watching the evening news where I saw some black South Africans sitting on a bench waiting for their turn to get the COVID-19 vaccine. My heart sank; I was so helpless, I sobbed. I called my daughter, who will be taking step one exam to complete her medical degree and become a physician to watch with me. This has been a hot topic in my household, and it should be time for change. My daughter has been involved in research and has evidenced the unfair treatment of blacks. I was outraged; I could not finish my dinner.

Africans Used for Testing COVOD-19 Vaccines

We witnessed the French doctors on television, not knowing that they were being taped discussing their plan to test the COVID-19 vaccine in Africans (Kossoff, 2020). Numerous relatives from South Africa and Zimbabwe have been calling us seeking advice about the vaccine trials, and we told them to absolutely not to take it. There goes another Tuskegee again. How long can black people suffer, not only racism, health disparities, but they are subject to many medical trials and vaccines that can harm them. No one knows the long term effects of the vaccine.

Two French doctors discussed on live television how a new COVID-19 vaccine under development should be first tested in Africa, "where there are no masks, no treatment, nor intensive care." (Kossoff, 2020)

One of them, Jean-Paul Mira, even compared Africans to prostitutes who were the focus of past AIDS studies. "We tried things on prostitutes because they are highly exposed and do not protect themselves," he said (Kossoff, 2020)

Growing up in Zimbabwe, Africa, I have witnessed many trials of medications and vaccines for HIV, oral contraceptives, to name a few. Many African countries are breeding grounds for big western pharmaceuticals, yet in the long run do not benefit from the proceeds. Many of the research participants do not consent and are not even aware of what is being given due to health illiteracy, which is a human right violation.

I have living relatives that have suffered the effects of such trials. I have an aunt who was given an oral contraceptive that turned out to be fatal. We only found out 10 years later when she was trying to have children. Another relative was given trials of polio vaccine which also resulted in harm. Women’s reproductive health is being violated, the old, poor and frail succumb to these big companies, even children are not exempt. African leaders are poor and greedy, they are so selfish that they sacrifice their people in exchange of cuff links, and a packet of sugar, what a disgrace!

Violation of Human Rights

Apartheid in South Africa and colonizers of African countries were characterized by systematic violation of human rights of the Black population (Barsdorf & Wassenaar, 2005). Succeeding ruling institutions perpetuated and enforced such violations (Barsdorf & Wassenaar, 2005). Consequently, Black South Africans may be apprehensive of scientific research in which the Black population are targeted as participants, regardless of the reason for them being selected. In America, Blacks are targeted as well due to poverty and low health literacy levels.

Increasingly, people worry that undue inducements for research participants in developing countries compromise the voluntariness necessary for informed consent (Emanuel, Currie, & Herman, 2005). In general, these research participants are poor, poorly educated, with access to few health-care services. They are often powerless, especially compared with pharmaceutical companies and researchers from developed countries.

What makes Africa Vulnerable

What makes individuals, groups, or even entire countries vulnerable? And why is vulnerability a concern in bioethics? A simple answer to both questions is that vulnerable individuals and groups are subject to exploitation, and exploitation is morally wrong. Vulnerable individuals can be harmed. African governments have to protect their people by raising awareness of exploitation and efforts to enhance the ability to protect their citizens from exploitation at the hands of powerful sponsors of research and not be enticed by expensive gifts.

Conclusion

James Marion Sims performed gynecological exams on enslaved black women and their children because he thought black women were less intelligent than their white counterparts (Sartin, 2004). The Tuskegee's black men were infected with syphilis without their knowledge (Reverby, 2012). Some people might say, why are you bringing this up, it was done long ago. But my point is to show that there is trend since slavery in using poor black people for research, many people were harmed, in case of good results, not compensated accordingly.

There is a trend of exploitation, and it is still taking place in America and poor African countries in 2020. Now that we can discuss racism, bigotry, oppression lets involve pharmaceutical companies. As nurses, we cannot participate in such activities, and it is our duty to educate and inform people in vulnerable populations about informed consent and participation in human trials. I am glad I can write about this and enlighten everyone without fear of retribution or being told by white people that racism is not real and it is an imaginary situation in black man/woman’s head. It's real, people, I am black and beautiful and a proud African .

When pharmaceuticals see poor black people, they see gold, free guinea pigs for research!

#Black Lives Matter - around the world. Stop medical exploitation on blacks!

Specializes in ER.
53 minutes ago, BeenThere2012 said:

She explained it in her post: Poverty pushes many for personal gain. Unethical practices of leaders go on all the time in the name of greed, and disrespect for their people. Why would these companies choose South Africans to do these trials? Because they know they can get many to participate out of fear and not realizing EXACTLY what they are agreeing to due to lack of education. Yes they do give consent, but while not fully understanding all the consequences.

Are they being paid? I know here in the US, people get paid to participate in trials.

I'll bet the going rate is cheaper in Africa. These pharmaceutical companies are all about profit!

56 minutes ago, BeenThere2012 said:

She explained it in her post: Poverty pushes many for personal gain. Unethical practices of leaders go on all the time in the name of greed, and disrespect for their people. Why would these companies choose South Africans to do these trials? Because they know they can get many to participate out of fear and not realizing EXACTLY what they are agreeing to due to lack of education. Yes they do give consent, but while not fully understanding all the consequences.

Are they being paid? I know here in the US, people get paid to participate in trials.

I'll bet the going rate is cheaper in Africa. These pharmaceutical companies are all about profit!

Specializes in Vents, Telemetry, Home Care, Home infusion.

Facts matter...

From the several websites I visited, people are signing up as volunteers due to a sense of patriotic duty or to help find a vaccine that will prevent family from getting virus. Wits University fact sheet states informed consent will be obtained, getting E diary to document symptoms, medical followup for 1 year.

Trial ongoing in Brazil and later US with same ChAdOx1-Cov19 vaccine serum obtained from UK Oxford University --- THE viral study being promoted here in US as most advanced vaccine study and expected to be ready for worldwide use by Winter/ Spring 2021.

Astra Zeneca will manufacture this vaccine if found safe and effective. Unable to find any info re payment for study participants. Karen

South Africa: Ox1Cov-19 Vaccine VIDA-Trial Fact Sheet

Quote

Research sites

Researchers at sites in Gauteng will begin testing the Covid-19 vaccine in human volunteers on Wednesday, 24 June 2020. The study is being undertaken in urban metropoles where the risk of SARS-CoV2 infection is high, and which are likely to be Covid-19 hotspots. The study may be extended to sites in Cape Town over the next few weeks.

Participants

The study aims to enrol 1,950 adult volunteers aged 18-65 years and who are HIV negative. They should not have tested positive for Covid-19 and should not be pregnant or breast-feeding, nor have previously participated in a trial with an adenoviral vaccine or received any other coronavirus vaccine.

The trial will also enrol a smaller number (50) of people living with HIV to examine the safety and how well they respond to the vaccine.

Participants will need to provide written informed consent to participate in the trial and they will remain on the trial for approximately one year....

... Participants will be given an E-diary to record any symptoms experienced for seven days after receiving the vaccine. They will also record if they feel unwell for the following three weeks.

Following vaccination, participants will attend a series of follow-up visits. During these visits, researchers will check participants’ observations, review the completed diaries, and take blood samples, which will be used to assess the immune response to the vaccine.

If participants develop Covid-19 symptoms during the study, they can contact a member of the clinical team who will assess them for infection. Should a participant become particularly unwell, they will be assisted to seek hospital care.

http://www.wits.ac.za/covid19vaccine/fact-sheet/

On 7/3/2020 at 2:49 PM, A Hit With The Ladies said:

I don't think it's ethical at all to test vaccines on African people, or any poor people on this planet. This is wrong.

Sadly, we live in a world that’s completely divided. God loves us all and it’s a ashame how one feel they should experiment on one particular group of people just to see how it would affect them before it’s FDA approved.

Specializes in Vents, Telemetry, Home Care, Home infusion.

Out of the lab and into people’s arms: A list of COVID-19 vaccines that are being studied in clinical trials

https://abcnews.go.com/Health/lab-peoples-arms-list-covid-19-vaccines-studied/story?id=71145250

Specializes in Critical care, tele, Medical-Surgical.

This clinical trial has not started yet

COVID-19 Vaccine (ChAdOx1 nCoV-19) Trial in South African Adults With and Without HIV-infection

Sponsor: University of Witwatersrand, South Africa

Collaborators: Medical Research Council, South Africa

Bill and Melinda Gates Foundation University of Oxford

Information provided by (Responsible Party): Shabir Madhi, University of Witwatersrand, South Africa

Brief Summary: A Phase I/II, double-blinded, placebo-controlled, individually randomized trial to assess safety, immunogenicity and efficacy of the candidate Coronavirus disease (COVID-19) vaccine ChAdOx1 nCoV-19 in adults aged 18-65 years living with and without HIV in South Africa. The vaccine or placebo will be administered via an intramuscular injection into the deltoid muscle of the non-dominant arm...

COVID-19 Vaccine (ChAdOx1 nCoV-19) Trial in South African Adults With and Without HIV-infection

Specializes in Critical care, tele, Medical-Surgical.
Quote

Healthcare worker unions explain their concerns

Access to appropriate personal protective equipment (PPE) has been a key concern for healthcare workers since early in South Africa’s COVID-19 epidemic. These concerns are becoming more acute as confirmed COVID-19 cases in South Africa this week shot up to over 100 000, with over 3 500 of these cases in healthcare workers.

But, as representatives from four different trade unions explain, access to PPE is far from the only issue. Amongst others, unions are also in a salary disputes with government and concerned about staff shortages, health worker safety, and the psychological strain workers are under.

According to Kevin Halama, Health and Other Services Personnel Trade Union of South Africa (Hospersa) spokesperson, the public healthcare system has many serious challenges.

“There is a problem with procurement of equipment. Workers need tools of trade but you find out when workers get to the hospital the equipment is faulty or not readily available or it’s just not up to scratch,” Halama says. “At times there is no medication. A number of facilities have poor infrastructure. Cables are exposed, poor town planning, buildings are dilapidated and overcrowded.”...... Access to appropriate PPE may not be the only issue, but it is certainly the issue of the moment...

COVID-19: Healthcare worker unions explain their concerns

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We can experience the best if people around us receive the best experience not exploitation by a few:

"Skin color and culture are meaningless anthropological artifacts continually pushed by those who wish to perpetuate the madness of differentiating humans based on exterior actions and appearance instead of appreciating both the commonality and diversity of our genetic makeup ".

"In addition to the South African study, similar and related studies are about to start in Brazil. An even larger study of the same vaccine of up to 30,000 participants is planned in the USA".

"It’s not Tuskegee again. You need to rethink that. You need to be able to accurately prove that is happening again"

We are living in a time when we are divided, with selfishness, seeing each other as competitors, refuting and questioning life experiences of blacks that have been documented since the beginning of time. I am going to rephrase my feelings as I have seen and have experienced in my lifetime and no-one can tell me how I feel as a black person . Another Tuskegee, yes, in my life, not yours that is how I visualize and see the injustices. I do not have to prove a point to anyone, history speaks for itself, maybe some people might take the time to educate themselves on the human trials done on blacks here in America and abroad. If skin color and culture are meaningless, then why the brutality and other racism acts including human trials being perpetuated. The ranting and refuting is the core of bigotry. That is the divide,just because you never experienced it so all you would like me to prove a point, pressure bursts pipes. My life experience gives validity and credibility to my point. Take a time to digest The whole point of this is:

"It does seem a touch unethical doesn’t it; even with informed consent you are exploiting someone’s vulnerability for lucre in the name of the greater good"

"I don't think it's ethical at all to test vaccines on African people, or any poor people on this planet. This is wrong."

Thank you

Dr Madenya

Quote

We witnessed the French doctors on television, not knowing that they were being taped discussing their plan to test the COVID-19 vaccine in Africans (Kossoff, 2020). Numerous relatives from South Africa and Zimbabwe have been calling us seeking advice about the vaccine trials, and we told them to absolutely not take it. There goes another Tuskegee again. How long can black people suffer, not only racism, health disparities, but they are subject to many medical trials and vaccines that can harm them. No one knows the long term effects of the vaccine.

Two French doctors discussed on live television how a new COVID-19 vaccine under development should first be tested in Africa, ”where there are no masks, no treatment, nor intensive care.” (Kossoff, 2020)

OP, what makes you say that the two French doctors weren’t aware that they were being taped? They were on TV after all, so what am I missing? From watching the interview on Youtube and reading the reference you provided, it appears that they were not discussing a new vaccine against Covid-19, but rather the ongoing trials to test the BCG vaccine’s efficacy against Covid-19. The trial is as I understand it underway in four European countries (the Netherlands, Germany, France and Spain) as well as in Australia and they discussed if running a parallel test in Africa would be a good idea.

I’m a bit confused by the paragraphs I quoted. What are the trials that your relatives have been calling you about. Is it the BCG one? (I don’t think that has been expanded to include any country in Africa). Or is it other trials that have nothing to do with the two French doctors you mention? Which is the vaccine that ”no one knows the long term effects” of?

The Tuskegee experiments are a stain on medical research history. They involved actively withholding treatment for an often fatal disease when an effective treatment had been discovered (along with a long list of other ethical transgressions). There is no doubt in my mind that it was racist.

But how is testing the efficacy of an existing or new vaccine against a pandemic disease that affect us all, in many different countries, the same as Tuskegee?

In my opinion, the same ethical rules should apply regardless of which country a trial takes place in. But surely you’re not suggesting that the entire African continent be excluded from all medical trials?

Specializes in BSN, RN, CVRN-BC.

Last time I checked South Africa is a sovereign nation that can make it's own decisions. Hopefully the rules regarding human testing in South Africa are similar to the rules here in the United States. These rules invoke protections for vulnerable populations such as prisoners and the poor. These rules are in place to ensure that unethical experimentation such as that done in Tuskegee are not repeated.

Quote

The Tuskegee’s black men were infected with syphilis without their knowledge (Reverby, 2012).

OP, I didn’t notice the quoted sentence the first time I read your post and I haven’t read Reverby’s book. Do you mean that the men weren’t informed regarding the disease they had or are you saying that they were infected by the ”researchers”? Does it really say in your referenced source that the Tuskegee men were intentionally infected, or does it say that they weren’t properly informed about their diagnosis?

As I understand it they were not properly informed regarding their diagnosis, it was referred to as ”bad blood” which could mean several different medical conditions, but wasn’t exactly precise. They weren’t treated in any meaningful way but were subjected to spinal taps for no good reason, under the pretense of treatment.

Generally a deeply unethical and horrible way to treat human beings. But I don’t think they were infected by the doctors. The doctors simply decided to do a prospective study of what happens if you don’t treat a serious disease. (Makes my blood boil thinking about it, seeing as penicillin was discovered to be an effective treatment during the time when the ”study” was ongoing).

There was another experiment on syphilis in Guatemala and they did infect over a thousand local individuals (psychiatric patients, prostitutes, soldiers and prisoners) with syphilis and other STDs, without the consent of a single study ”participant”. It seems they even did experiments on children, although I’m not clear on whether they were among those who were infected on purpose.

The Guatemala experiments (1946-1948) were led by an American physician who had also been involved in the later stages of the Tuskegee experiments.

Some of the details described in the wiki link below are quite horrific. The cruelty these doctors showed in the name of ”science” is deeply disturbing.

Guatemala syphilis experiments - Wikipedia

Guatemala syphilis experiment | American medical research project- Britannica

OP, I realize that you might feel like I’m nitpicking here, but facts do matter. The topic, racism, that you write about is extremely important and as I’m sure you know better than I, is very much real. I think it deserves an accurate portrayal of the facts as they are. I’m in no way trying to minimize the seriousness of what was perpetrated against the men (and their families) in the Tuskegee experiments. What was done to them was very unethical and it sickens me.

If I’ve misunderstood the circumstances regarding the Tuskegee experiment, I apologize.

On 7/5/2020 at 11:29 AM, munyaradzi rwakonda said:

We can experience the best if people around us receive the best experience not exploitation by a few:

"Skin color and culture are meaningless anthropological artifacts continually pushed by those who wish to perpetuate the madness of differentiating humans based on exterior actions and appearance instead of appreciating both the commonality and diversity of our genetic makeup ".

"In addition to the South African study, similar and related studies are about to start in Brazil. An even larger study of the same vaccine of up to 30,000 participants is planned in the USA".

"It’s not Tuskegee again. You need to rethink that. You need to be able to accurately prove that is happening again"

We are living in a time when we are divided, with selfishness, seeing each other as competitors, refuting and questioning life experiences of blacks that have been documented since the beginning of time. I am going to rephrase my feelings as I have seen and have experienced in my lifetime and no-one can tell me how I feel as a black person . Another Tuskegee, yes, in my life, not yours that is how I visualize and see the injustices. I do not have to prove a point to anyone, history speaks for itself, maybe some people might take the time to educate themselves on the human trials done on blacks here in America and abroad. If skin color and culture are meaningless, then why the brutality and other racism acts including human trials being perpetuated. The ranting and refuting is the core of bigotry. That is the divide,just because you never experienced it so all you would like me to prove a point, pressure bursts pipes. My life experience gives validity and credibility to my point. Take a time to digest The whole point of this is:

"It does seem a touch unethical doesn’t it; even with informed consent you are exploiting someone’s vulnerability for lucre in the name of the greater good"

"I don't think it's ethical at all to test vaccines on African people, or any poor people on this planet. This is wrong."

Thank you

Dr Madenya

Absolutely this! I don't understand why people are acting like they don't understand what you're saying, especially about the Tuskeegee experiment when it's been well documented, movies and everything. It also happened to Henrietta Lacks and her family, which resulted in HeLa cells which have been used MANY times throughout medical history and her family weren't compensated, were tested, prodded, poked, and were never informed of why, nor the use of Lacks' cells. Companies have made billions from HeLa cells yet her family were poor. This is one of many examples. None of this is new but somehow people still act like it's impossible and it's nothing major. As a Native/Black person, it's major!

I completely get it.

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