Jump to content

Zosyn

Medications   (5,902 Views | 15 Replies)

1,007 Profile Views; 10 Posts

Hey everyone. Brand new RN here. Quick question. Does anyone have any advice for reconstituting zosyn into 100 mL of NS? I ran into the problem twice of the zosyn clumping at the bottom and I had to beat the side of the jar with my hand for about 5 minutes to finally get it to mix. Is there an easier way or is this just one of the many struggles we often deal with? Thank you in advance!

Share this post


Link to post
Share on other sites

traumaRUs has 27 years experience as a MSN, APRN, CNS and specializes in Nephrology, Cardiology, ER, ICU.

165 Articles; 21,045 Posts; 195,098 Profile Views

Moved to pt meds

Share this post


Link to post
Share on other sites

RainMom has 7 years experience.

1,093 Posts; 24,061 Profile Views

That's just the nature of Zosyn; it's notorious for not being easy to mix. Just keep shaking it until all the clumps are gone. Allow yourself several minutes to mix before taking to the pt's room to administer.

Share this post


Link to post
Share on other sites

Rose_Queen has 15 years experience as a BSN, MSN, RN and specializes in OR, education.

12 Followers; 4 Articles; 9,558 Posts; 111,291 Profile Views

We get premixed bags from the manufacturer. Is that an option that could be explored?

Share this post


Link to post
Share on other sites

meanmaryjean has 40 years experience as a DNP, RN and specializes in NICU, ICU, PICU, Academia.

4 Followers; 7,632 Posts; 66,623 Profile Views

Pop the seal and flood the medication part- then walk away for about half an hour.

Share this post


Link to post
Share on other sites

akulahawkRN has 5 years experience as a ADN, RN, EMT-P and specializes in Emergency Department.

2 Followers; 3,447 Posts; 28,081 Profile Views

That's just the nature of Zosyn; it's notorious for not being easy to mix. Just keep shaking it until all the clumps are gone. Allow yourself several minutes to mix before taking to the pt's room to administer.

On top of giving myself a few minutes to mix the stuff, one thing I also do is tap the container to knock the powder loose. Once that's done, then I'll actually start mixing the stuff. Sure it takes a few minutes but at least by knocking the stuff loose you don't have to worry about those darned little clumps that just stick to the bottom...

Now ziprasidone... that stuff just takes forever. Order it stat and it'll be ready tomorrow. (At least it seems like it!)

Share this post


Link to post
Share on other sites

amoLucia specializes in LTC.

2 Followers; 5,733 Posts; 47,702 Profile Views

On top of giving myself a few minutes to mix the stuff, one thing I also do is tap the container to knock the powder loose. Once that's done, then I'll actually start mixing the stuff. Sure it takes a few minutes but at least by knocking the stuff loose you don't have to worry about those darned little clumps that just stick to the bottom...

This is the trick for just about ALL powder meds for reconstitution.

Always loosen up the powder first.

Share this post


Link to post
Share on other sites

Zyprexa has 2 years experience.

204 Posts; 3,192 Profile Views

Oh the joys of Zosyn (and Geodon)! Giving Geodon IM STAT really doesn't exist because it takes literally 10min to reconstitute :yawn:

Share this post


Link to post
Share on other sites

91 Posts; 1,846 Profile Views

HA HA, I asked that same question to my DON first time I had to hang Zosyn. I was literally beating the palm of my and to death for a while to get all the clumps out. Apparently from what I was told that's just the way it is.

Share this post


Link to post
Share on other sites

imintrouble has 16 years experience as a BSN, RN and specializes in LTC Rehab Med/Surg.

2,401 Posts; 51,509 Profile Views

I start shaking even before the diluent gets to the vial. A variant of the shake the powder first method.

It still takes a while, but getting the diluent to the bottom under the powder helps a little.

Mostly I just recognize I have Zosyn to hang, get it mixed early, and let it sit until I need it.

Share this post


Link to post
Share on other sites

28 Posts; 966 Profile Views

Yes, once you've reconstituted it, put it in an inner pocket. Your body heat helps to dissolve the clumps and it works pretty quickly!!!

Share this post


Link to post
Share on other sites
×

This site uses cookies. By using this site, you consent to the placement of these cookies. Read our Privacy, Cookies, and Terms of Service Policies to learn more.