A debate came up at work regarding Vimovo and other pills that combine two generics, the combination is considered a new drug and given exclusivity. Vimovo is naproxen and esomeprazole in one pill (Aleve and Nexium), a month's supply of generic naproxen and exomeprazole in separate pills costs about $40, a month's supply of Vimovo ranges from $2,300 to $3,000.
Even though the active ingredient is the same, not all formulations have the same effect, some patients absorb warfarin more predictably with some formulations than with others, so there are times where using the brand name formulation makes a difference. The justification for Vimovo and other generic combination pills is only that it's easier to take one pill instead of two.
The debate that came up was if you were doing a med rec for instance, and a patient told you they take this drug, would you use the opportunity to point out that the same medications are available separately at 1/60th the price? Would you suggest they ask their doctor why they need the two medications in one pill instead of two? Or would you just stay out of it and not mention it at all?