Published Jun 30, 2008
momathoner09, BSN, MSN, APRN
251 Posts
I have a quick titration question- I am taking my nclex TOMORROW and can't seem to figure out this problem. Thank you in advance.
The MD orders: Titrate Dopamine to keep pts systolic BP greater than 90mmHg
Pt weighs 150 lbs
The Dopamine is running at 5 mL/hr
The concentration of Dopamine is 800 mg in 250 mL D5W
How much dopamine is the pt receiving per minute??
(The answer is 3.92 mcg/kg/min)
MsNursingStudent
15 Posts
are you sure you have all parts to the question?
Kiringat
239 Posts
ok. i think i got it.
the formula is:
rate (ml/hr) [color=#330000]x concentration ("unit"/ml)
time (60 min/hr) [color=#330000]x weight in kilograms
so plugging in the info:
5 (ml/hr) x 320 mcg ("unit"/ml)
60 (60 min/hr) x 68 kg
that gets you 1600/4080 = 3.92
i think.....
BebobthefrogFNP
110 Posts
ok. i think i got it. the formula is:rate (ml/hr) [color=#330000]x concentration ("unit"/ml) time (60 min/hr) [color=#330000]x weight in kilograms so plugging in the info:5 (ml/hr) x 320 mcg ("unit"/ml)60 (60 min/hr) x 68 kg that gets you 1600/4080 = 3.92i think.....
that's what i got too but, i did dimensional analysis.
Thank you!!!! Hopefully I don't have too many of these crazy questions tom. My friend had 6 titration calculations on her NCLEX. I will fall out of my chair if that happens...literally
2008China
25 Posts
should be: 5 (ml/hr) x 3200 mcg ("unit"/ml)
then16000/4080 = 3.92
OrchidRN08
7 Posts
why do you have to change your mg to mcg? is that part of the formula? i know she gave the answer as 3.92 mcg/kg/min but why can't it be mg/kg/min?????
Italia13 RN
153 Posts
yea i am confused too. If i would of got this question on boards I would of for sure got it wrong becasue I would of done mg/kg/min. How do you know from the question u have to convert to mcg?
suzanne4, RN
26,410 Posts
Best of luck on your exam. But you should have everything already put away and should not be reviewing ever the day before the exam.
Hands and Heart
217 Posts
The drug order for dopamine (and some other titrated drugs) is usually given as mcg/kg/min. You can also look at the units given in the answer choices to know what units in which you have to have your final answer.
nursemich
322 Posts
[color=#660000]titration: flow rate
[color=#660000]calculating flow rate (ml /hr): key elements:
[*] time is constant (60 min/hr).
[*] weight of the client is expressed in kilograms.
[*] concentration of the infusion.
formula to calculate flow rate:
[color=#330000]example:
[color=#0080c0]for the client whose weight is 130 lbs and has dopamine ordered at 8 mcg/kg/min, what rate should the infusion pump be set for a solution of 400 mg dopamine in 250 ml d5w?
[color=#330000]critical information:
[color=#330000]tip: 1) convert wt to kg. 130 / 2.2 = 59.09 kg
2) find concentration of dopamine in 1 cc.
[color=#0080c0]400/250 = 1.6cc[color=#0080c0]
3) concentration is 1.6 mg /cc. convert the mg to micrograms.
[color=#0080c0]1.6 (mg) x 1000 (mcg per 1 mg) = 1600 mcg/cc.
[color=#0080c0]now that you have gathered all the information, plug it into the formula:
8 ("unit"/kg/min) [color=#330000] x 59.09 (wt in kg) [color=#330000]x 60 (min/hr)
1600 ("unit" / ml)=28363.32 1600x=17.727[color=#ffffff]17.727 or 18 ( ml/hr) will dialed on the pump.
nursingpower
66 Posts
i know i am very late but to make sense to people who may come upon this question and still want an answer, i hope this helps.
in a critical care setting (icu, er, sdu) there are potent drugs that need to watch closely by rn's. it is a matter of life or death. if we give to little or too much, the room for error is small. the patients body weight is critical because that makes the difference from patient to patient. micrograms is used according to the manufactuers instructions.
vasoactive drugs by definition are drugs that elicit vasoconstrictive or vasodilative action on blood vessels. if you look in your drug books (i have mosby's ndr) you will notice under the dosage/route/iv section that the instructions for iv route is to give in mcg/kg/min or mcg/min. if you notice in the pharmacokinetics section many of these drugs (iv form) have a very fast onset and short duration and half-life. these are some drugs that are titrated in critical care settings and their onset, duration and half-life straight from the nursing drug reference. (all of these drugs are ordered in mcg/min or mcg/kg/min according to the drug reference.)
nitroprusside o: 1-2min d: 1-10 min h: 2min
dopamine o: 5 min d:
dobutamine o: 1-2 min d: peak 10 min h:2 min
nitroglycerin o: 1-2min d: 3-5min h: 1-4min
in my opinion it would make sense to order these small doses (mcg) per minute because the effects last a few minutes and hemodynamics could change a little or alot from min to min. we have to do all the calculations just to put them on pumps. i am just glad we don't have to titrate manually..lol. what did they do before pumps?