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Think EpiPen. It works rapidly. Since no IV established it would waste time starting an IV with possibly collapsing vasculature and dropping BP that can occur with anaphylaxis
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Remember that Epi is a short-acting drug, and that the duration of effect of the bee sting may out last the duration of action of the Epi-Pen. Once the Epi-Pen is given and effects are seen, you would begin IV insertion for follow-up doses of Epi, Benadryl and Steroids that will be necessary to stabilize the patient over the longer term.
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In theory, IM through EpiPen. It takes exactly 5 seconds to get the drug working. Plus, excruciating pain from this injection adds stress responce (seriously, it hurts like ****, and it is right the case when pain is good). In the next 5 minutes, one can get an IV and start fluids, steroids and antihistamines.
It is true that Epi us a short acting thing, that's why it is prescribed in two syringes pack, and more experienced patients usually carry double packs.
In practice, though, the question is more interesting. I was asked more than once how epinephrine is supposed to work when there is no systemic blood pressure to speak of and therefore no circulation to bring the drug to the bloodstream. From my personal experience, in case of primary systemic reactions (the rare and extremely dangerous kind when massive surge of histamine and mediators causes critical drop of blood pressure within one or two minutes, and death from cardiac arrest within next 3 to 5 minutes, with respiratory and other symptoms just not yet developing) EpiPen is much less effective.
I would rather be careful with IV epinephrine in the field and without good monitoring of vitals. The dramatic surges of blood pressure are known to cause strokes on more aged patients, and 0.3 mg of Epipen is quite a dose to be given as a quick push.
JuliusSeizure
24 Posts
A patient comes in to the urgent care center and states that she has been stung by a bee. She complains of shortness of breath and dizziness. She is pale and loses consciousness in the waiting room. The receptionist screams for help and calls 911. The nurses recognizes that which of the following medications should be considered first?
A.) Diphenhydramine (Benadryl)
B.) Phenytoin (Dilatin)
C.) Epinephrine IV
D.) Epinephrine IM
It looks like an emergency situation to me, so naturally I would go with IV for fastest route, but the issue here is, does she have an IV site? If not I go with IM.