Be persistent and follow-up after you've filled out an application or sent your resume. Call the recruiter every other week to check your status. If possible, try to find a manager's name & contact info and introduce yourself.
Be open to all kinds of positions even though it's not your dream job. Have you tried nursing homes? long term care? private offices? clinics? Also, look for healthcare recruiting agencies (most of the time they want experience nurses but flu season will start soon and you may get a flu shot job)... although it's a temporary job, at least you're doing something with your license.
Have you tried volunteering at a hospital? If you have the money to spend, you can go ahead and advance yourself by taking ACLS, IV therapy, PALS, NRP... depending on what your interest is. Also, you may look into joining associations like american nurses association, med-surg association.... etc depending on your interest.
I graduated last year and I never gave up job hunting. Don't give up! Good luck :)