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Discussion

peripheral neuropathy

has anyone ever heard of perpheral neuropathy in a pt who is not diabetic? she c/o pain and tingling in her feet and toes , wears ted hose when at work. doc put her on lyrica..... seems to help.... but i have never heard of this without being diabetic.....could it be a form of reflex symapthic dystrophy? thank you all in advance

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I can think of a couple of patients I've encountered with that diagnosis, with no hx of diabetes.

There seems to be a lot of variability in the diagnosis & treatment of chronic, idiopathic pain -- you'll see lots of different diagnoses from different clinicians.

Although it is more common in diabetic, it is also found in non-diabetics. People who are overweight and/or on their feet a lot are getting more susceptible to it even without diabetes being a factor.

Glad her doc put her on lyrica. Many want to use neurontin because it is cheaper but it does not seem to do as well but I have seen a few pts that did ok on just neurontin.

  • Experts

Chemotherapy induced peripheral neuropathy. I also have peripheral neuropathy from a pinched S1 nerve on the left side. When I was getting my chemo I talked to several patients who had gotten oxaliplatin--this is a side effect of this drug. I got it and still have numb feet and weird sensations in the skin of my legs and arms. The neurologist tried me on Lyrica, but it made me feel like I was vibrating all over similar to what Gabitril did when I took that, so that was the end of Lyrica for me.

I've got an senior family member who has diminishing sensation in his extremities. Been tested for diabetes (several times) and seen a specialist or two (eg neurologist), but no positive diagnosis made, besides "looks like peripheral neuropathy." No meds have been prescribed as there's no pain or tingling, etc, but the lack of sensation is causing problems with balance and safety (eg driving). So, it does seem that PN can occur in the absence of DM. I'd love to hear of other possible causes of this condition and any potential treatments for improving sensation or preventing worsening - as opposed to just treating the painful symptoms.

I guess the way to look at it might be: is there more than one way to cause nerve damage in the peripheral nervous system? What are they?

And also, what is the mechanism by which diabetes causes neuropathies?

Look at the questions behind your question....

:)

  • Author
I guess the way to look at it might be: is there more than one way to cause nerve damage in the peripheral nervous system? What are they?

And also, what is the mechanism by which diabetes causes neuropathies?

Look at the questions behind your question....

:)

are you in RN school? i am a RN and have been a nurse for 23 years....

what do you think.. i've been a nurse for 23 years and haven't seen this at all....

you have great questions, you must be in school....

thank you for your input , i appreciate all your comments

Other causes:

-People with Vitamin deficiency, like B12 or folate. Also seen in Alcoholics r/t poor diet which results in vitamin deficiency.

-Trauma or pressure on a nerve (nerve entrapment). Can be caused by repetitive movements

-Autoimmune diseases

-Hypothyroidism

-Lyme Disease

GOOGLE or ASK.com are great places for more answers. Just search Diabetic Neuropathies...you'll get thousands of hits.

  • Author
Other causes:

-People with Vitamin deficiency, like B12 or folate. Also seen in Alcoholics r/t poor diet which results in vitamin deficiency.

-Trauma or pressure on a nerve (nerve entrapment). Can be caused by repetitive movements

-Autoimmune diseases

-Hypothyroidism

-Lyme Disease

GOOGLE or ASK.com are great places for more answers. Just search Diabetic Neuropathies...you'll get thousands of hits.

hmmm that is very interesting, she does have a history of lime diease... my dear i think you got it... that makes lost of sense..

thanks for teaching and old nurse something new... give yourself a big hug for me:yeah:

And the last line of the Mayo clinic info notes that if it's not related to DM, one may never identify the cause... still lots of medical mysteries to be solved!

My mother has neuropathy in her feet and has an "official" diagnosis of Charcot Joint. She has been tested for diabetes many times and has never had even a hint of the disease. They say they will never know what caused it but the bones in her feet have basically disentigrated and she has rocker bottom soles. She may never walk for more than a few hundred feet again and has to have her feet checked on a regular basis as if she were diabetic. Its very frustrating.

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I've had some sort of neuropathy in my right foot for years. There's no pain, but the numbness has progressed from the outside of the baby toe to the entire outer part of the foot, the sole, and the middle toe. I also have some venous stasis in the same leg.

However, I don't think it has anything to do with diabetes, because my FBS was always in the 85-95 range until this year, when it was 108 and my doctor pronounced me "prediabetic".

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