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ok. i think i got it.the formula is:
rate (ml/hr) [color=#330000]x concentration ("unit"/ml)
time (60 min/hr) [color=#330000]x weight in kilograms
so plugging in the info:
5 (ml/hr) x 320 mcg ("unit"/ml)
60 (60 min/hr) x 68 kg
that gets you 1600/4080 = 3.92
i think.....
that's what i got too but, i did dimensional analysis.
ok. i think i got it.the formula is:
rate (ml/hr) [color=#330000]x concentration ("unit"/ml)
time (60 min/hr) [color=#330000]x weight in kilograms
so plugging in the info:
5 (ml/hr) x 320 mcg ("unit"/ml)
60 (60 min/hr) x 68 kg
that gets you 1600/4080 = 3.92
i think.....
should be: 5 (ml/hr) x 3200 mcg ("unit"/ml)
60 (60 min/hr) x 68 kg
then16000/4080 = 3.92
[color=#660000]titration: flow rate
[color=#660000]calculating flow rate (ml /hr): key elements:
[*] time is constant (60 min/hr).
[*] weight of the client is expressed in kilograms.
[*] concentration of the infusion.
formula to calculate flow rate:
[color=#330000]example:
[color=#330000]critical information:
[color=#330000]tip: 1) convert wt to kg. 130 / 2.2 = 59.09 kg
2) find concentration of dopamine in 1 cc.
[color=#0080c0]400/250 = 1.6cc[color=#0080c0]
3) concentration is 1.6 mg /cc. convert the mg to micrograms.
[color=#0080c0]now that you have gathered all the information, plug it into the formula:
why do you have to change your mg to mcg? is that part of the formula? i know she gave the answer as 3.92 mcg/kg/min but why can't it be mg/kg/min?????
i know i am very late but to make sense to people who may come upon this question and still want an answer, i hope this helps.
in a critical care setting (icu, er, sdu) there are potent drugs that need to watch closely by rn's. it is a matter of life or death. if we give to little or too much, the room for error is small. the patients body weight is critical because that makes the difference from patient to patient. micrograms is used according to the manufactuers instructions.
vasoactive drugs by definition are drugs that elicit vasoconstrictive or vasodilative action on blood vessels. if you look in your drug books (i have mosby's ndr) you will notice under the dosage/route/iv section that the instructions for iv route is to give in mcg/kg/min or mcg/min. if you notice in the pharmacokinetics section many of these drugs (iv form) have a very fast onset and short duration and half-life. these are some drugs that are titrated in critical care settings and their onset, duration and half-life straight from the nursing drug reference. (all of these drugs are ordered in mcg/min or mcg/kg/min according to the drug reference.)
nitroprusside o: 1-2min d: 1-10 min h: 2min
dopamine o: 5 min d:
dobutamine o: 1-2 min d: peak 10 min h:2 min
nitroglycerin o: 1-2min d: 3-5min h: 1-4min
in my opinion it would make sense to order these small doses (mcg) per minute because the effects last a few minutes and hemodynamics could change a little or alot from min to min. we have to do all the calculations just to put them on pumps. i am just glad we don't have to titrate manually..lol. what did they do before pumps?
momathoner09, BSN, MSN, APRN
252 Posts
I have a quick titration question- I am taking my nclex TOMORROW and can't seem to figure out this problem.
Thank you in advance.
The MD orders: Titrate Dopamine to keep pts systolic BP greater than 90mmHg
Pt weighs 150 lbs
The Dopamine is running at 5 mL/hr
The concentration of Dopamine is 800 mg in 250 mL D5W
How much dopamine is the pt receiving per minute??
(The answer is 3.92 mcg/kg/min)