Slamming in IVP meds and Running Incompatible Meds Together: Is it as bad as they say

Nurses Medications

Published

When I graduated from nursing school and worked at my first hospital, I was very diligent about pushing meds at the recommended rate; I remember taking up to 4 to 5 minutes just to push dilaudid, morphine, and demerol. Solumedrol was another one that was pushed slowly. In those days I remember actually holding my watch up to the syringe to make sure I wasn't pushing too much too quickly.

Since that time, I moved to a hospital where no one times themselves as they push meds and since transitioning to critical care, I was told by my colleagues that the "ICU way" is just to push everything fast. I'm not talking about critical situations such as codes either - I am talking about just routine doses of versed for conscious sedation, zofran for nausea, haldol for agitation, fentanyl and pretty much any narcotic too. Everyone just basically slam in the meds then leave the room then continues on their merry way.

Another thing that I see go on a lot is the running of incompatible meds together. We use micromedex which is an online IV compatibility library and what I've found is that a lot of meds that are supposedly incompatible actually do run together. I was always taught that incompatible meds form a precipitate due to acidity or alkalinity of the meds or fluids. However, I have watched nurses set up y-porting 3 or 4 meds that are supposed to be incompatible and they run just fine. Why is that? I even saw one nurse push dilaudid through a line that had TPN & lipids which I thought was incompatible with everything.

Does anyone else witness or participate in these "bad practices?" What do you think of them? I'm still confused on how the incompatible meds run together, personally. Nonetheless, I avoid it.

Specializes in Emergency Room.
At everywhere I've worked the policy is to just inject the diazepam even if it mixes with other fluids in the line and precipitates (turns white), since it resuspends completely and immediately when it mixes with even a small amount of plasma.

Other than giving it IM I've never actually figured out how it would be given IV without touching any other IV fluid (the only thing it doesn't precipitate in are things like polyethylene glycol).

Thank you for sharing this. We were just discussing this at work a couple of nights ago. I noticed the date of the study you referenced is 1978. A (quick) internet search didn't reveal any significant studies since then on this matter. Seems like the best practice would be to give it undiluted as close to the IV insertion point as possible and to push slowly.

Specializes in ICU.
A very experienced ED nurse told me that if IV metoprolol is pushed too fast, it can "bottom out" a patient's pressures, making them ineligible to get other meds they might really need for heart rate irregularities/MI.

In the ICU, maybe this would translate to unnecessary pressor boluses?

I'm not worried about slamming in metoprolol because it might drop the patient's BP or HR... I'm concerned about slamming in metoprolol because slamming in a beta blocker can send someone into total heart block. Watched a coworker do that to a patient once. You really don't want to be the idiot who has to roll out the crash cart and set the defibrillator to pacing mode because you were too impatient with the beta blocker. Your coworkers will never let you live it down.

That being said, cardiac meds and diuretics are really the only things I give over the recommended times. Most everything else gets pushed in quicker.

And regarding TPN - I usually leave that on a line by itself, but I will run my electrolye replacements y-ed in with it. If you think about what TPN actually is, you know you will never have to check to see if it is compatible with electrolytes. My preceptor gave me that tip once and it has saved me a lot of time since then!

Specializes in Acute Care - Adult, Med Surg, Neuro.

I always push my IVP medications over at least 2 minutes because I'm a rule-follower. I know many other nurses don't because I've had patients complain to me that I'm "pushing the Dilaudid too slow." Narcotics can make patients nauseated and uncomfortable if pushed too fast, and Zofran too fast can give people a wicked headache. Solu-Medrol gives what I've heard other nurses refer to as "fire crotch"

I check compatibility and won't risk hanging two incompatible solutions together. I did the Valium precipitate thing one time right off of orientation and that scared me enough to be very cautious.

I have never ran anything with TPN/lipids because of the increased infection risk by entering the line, not because of compatibility concerns.

Specializes in Oncology; medical specialty website.

Let me tell you what it feels like to have someone whomp dilaudid through your line...terrible.

A nurse did that to me, and I felt like I was going to stop breathing and pass out, and I'm not opiate naive. I think she pushed it in in under 5 seconds.

I watch the time on push meds. Just because it worked out OK for one patient doesn't mean it will the next time. Better safe than sorry.

To answer the OP's title question: YES!

Anyway...

...agree with many previous posters. check compatibilities, call your pharmacist, read the recommended push times. I agree w/TPN and lipids being dedicated to their own lumen. I try to advise the MD's to always get a double or triple lumen (rather than single) CVC placed for this very reason. It's reasonable to assume that this very sick pt will need to get multiple incompatible meds.

I try to push a little of the med, then chat, maybe get a set of vitals, push a little more....and so on. It's so difficult with time constraints. I am guilty of pushing zofran too quickly. I never received pt feedback that they got a headache. But now I know :) I love reading all of your responses! As far as I recall, we definitely need to filter mannitol, phenytoin, and tpn/lipids. any others I should watch out for?

Specializes in Vascular Access.

Every nurse should be concerned and assess whether or not compatibility exists between two drugs going into the same syringe, or going into the same IV tubing. As far as TPN is concerned, it is not just compatibility that one should be worried about. Infections are also of utmost concern. The lumen used for TPN should be TPN dedicated. No other medications, or solutions x Lipids should ever be piggybacked into this line. If the staff placing the PICC knows that TPN will be in the future of the patient, a single lumen catheter is inappropriate.

It really makes a big difference on the situation. What meds are you pushing and why.

For sedation and pain meds if the reason for the medication is to have the patient sedated quickly so a procedure can be done. (Or if they are in severe acute pain.)

The patient must be on cardiac, BP, pulse ox, and supplemental oxygen, a crash cart is available. The patient must be continuously monitored by a nurse during the procedure and closely watched afterwards. Then the drugs can be safely given rapidly.

If the patient is on a regular med/surg floor, not on continuous monitoring, sure MAYBE if the nurse knows the patient, they have been on these meds for several days, they have been stable...etc. maybe the can be pushed a little fast. But if you don't know the patient they are not on any monitors, I would go as slow as the books recommend.

Specializes in CCU, SICU, CVSICU, Precepting & Teaching.

Meds that are incompatible in the same syringe may be OK Y'd together near the site, or running through a carrier. I actually DO watch the clock when I push meds, even after 38 years.

+ Add a Comment