Overmedication: The Silent Killer Of the Elderly

Overmedicating the elderly in America is a common problem. As nurses, we have seen the elderly with a long medication list, and sometimes they cannot tell you what some of the medications are for. Not only are the elderly often overmedicated, medications can be used as chemical restraints in the older population, especially those who do not have an advocate to look after them. Nurses Announcements Archive

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The healthcare system in America has developed into one with the ability to prolong quality of life. When it comes to the older population who often take multiple medications due to chronic issues, they can end up with duplicate medications for the same issue. Frequently seniors don't ask questions of their caregivers. They are of the generation in which the doctor knows best, not recognizing that they need to be their own advocates.

Overmedication of the elderly is a complicated problem. According to the article, "Overmedicating Our Elders", over half of the adults in America take prescription drugs, and within that group, the average number of scripts was four. In fact, the amount of prescriptions filled by Americans 'increased 85 percent from 1997 to 2016". That's a tremendous increase, raising the question whether patients are being treated for conditions they may not have, and what is the motivation behind so many medications.

There has been an increase in lawsuits in our society that may answer for some of the physicians feeling they must prescribe a medication in situations that aren't necessary to avoid litigation. Often times, this leads to alleviating symptoms rather than treating the underlying problem.

According to the article, dementia and alzheimers are often treated with the wrong medication. Behavior in patients with these diseases can be challenging, leading to doctors prescribing antipsychotic to patients in nursing homes with no diagnosis of schizophrenia for example. Overmedication of the elderly can be misdiagnosed as dementia or even alzheimers disease. Unfortunately this has regularly taken the place of physical restraints, replacing them with chemical.

In 2018, the Human Rights Watch published a research project that revealed that 179,000 patients in nursing homes were given antipsychotic medications with the purpose of controlling their behavior. With the awareness of this, Medicare and Medicaid are asking for a 15 percent reduction in this practice by 2019. The FDA issues antipsychotic drugs with a warning - "Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death".

Another concern with the elderly and medications is the far ranging side effects. Multiple medications increases the chance of side effects and then the patients are treated for the side effects with more medication. Once a patient is discharged from the hospital, more medications are prescribed. Over a few years, the patient continues to have a growing list of medications. Being older increases the chance of side effects, misuse or overdose related to the slower eliminations of medications.

An example of the latter is found in an article called, "Overmedication in the Elderly, Polypharmacy a Growing Problem Among Seniors". An 83 year old female was admitted to the hospital for asthma. The steroids she is given cause her blood pressure to elevate, so she was given a blood pressure medication which made her dizzy. Her ankles had become swollen and she was given a diuretic that caused her potassium to lower dangerously. She was given potassium to combat the hypokalemia. And the cream on the coffee is that she was given an arthritis medication while in the hospital that eventually gave her stomach ulcers. The escalation of medications and side effects can reach a level that is dangerous or maybe deadly to the elderly.

"Clinical inertia" is a term Dr. Donovan Maust from the University of Michigan uses to describe when a physician is reluctant to change or discontinue a medication given to a patient by another physician.

Then there is the opioid overprescribing that has lately been in the news, gaining a lot of public attention. Almost ten years ago, the American Geriatric Society put out recommendations to physicians to decrease the use of over the counter medications such as ibuprofen, that they should prescribe opioids for their patients with "moderate to severe pain". We can see the manifestation of this in our society now as the battle to decrease the overuse is fought.

Cost is a large factor for the elderly who are on a fixed income to be able to buy their medications. In the article, "Prescriptions Drugs, Practicing Physicians, and the Elderly", the authors state that "price and quantity demanded are inversely related; if patients pay less for medications, they will they will demand more prescriptions. The physician will respond by writing more prescriptions". This leaves us scratching our heads, there needs to be more education on the patient's end and the physician should feel empowered to tell a patient no regarding a script that is not necessary. Drug utilization review programs are set up to make sure the process of prescribing and dispensing of medications meet guidelines. They don't micromanage a single patient's medications, but gather data to modify patterns of prescribing.

The concept of deprescribing has become a slow grass roots movement in which duplicate medications are discontinued, as well as unnecessary medications. Dr. Ranit Mishori a professor of medicine at Georgetown University puts it this way, "we're taught as physicians to prescribe drugs. We are definitely not taught how to take people off meds".

There are many dangerous downsides to overmedication of our elderly population. We see it in our family members, our patients clinics, and in the hospitals. As the trend for minimizing medications slowly takes hold, we need to be aware of the patients without advocates especially in nursing facilities. We can make recommendations to our physicians and the patients families to help decrease the overuse of medications.

Have you encountered this in your practice? Tell us what you see being done to counteract overprescribing.

References

Lavizzo-Mourey, Risa J. & Eisenberg, John M. "Prescribing Drugs, Practicing Physicians, And The Elderly." Feb 27, 2018. HealthAffairs.org. Web. Feb. 27, 2018.

Mercola, M.D. "Overmedicating Our Elders". Feb. 2, 2018. Mercola, Taking Care Of Our Health. Web. Feb. 27, 2018.

"Overmedication In The Elderly; Polypharmacy a Growing Problem Among Seniors". 2018. Parentgiving.com. Web. Feb. 27, 2018

Specializes in Surgical, quality,management.

I see this constantly in my ward. About 20% of our acute community falls with fractures are due to multiple medications. Most times as a clinical group we discuss with families about stopping at least one HTN agent and often their lipid lowering drugs as well.

With patients who come in with upper GI bleeds post recent CABG or stents requiring DAPT, those that are not gastroscoped pre op are often presenting with bleeds due to DAPT. We cannot stop the treatment so we end up adding more meds on!

Specializes in ICU, LTACH, Internal Medicine.
Oh no, I'm that nurse! I definitely am a "less is more" advocate when it comes to medication for the folks in my care (I work at a provider of group homes for adults, many elderly, with intellectual disabilities), but I draw the line at no BM in 3 days. I've seen too many histories of small bowel obstructions and too many instances of hospitalizations with bowels chock full of stool. Maybe if I had the luxury of being able to assess every single person who hadnt had a BM in a day or two, but their day-to-day care is performed by unlicensed personnel with 32 hours of med training.

Is it "in the literature" that 3 or 4 days without a BM has better outcomes than an aggressive 72-hr bowel regimen of suppositories and enemas?

Here is old but good quality prospective study about stool patterns in community. Apparently, there are some folks walking around with doing that once a week with no ill effects, and nobody frets about it.

http://gut.bmj.com/content/33/6/818.full.pdf

Also, constant using of laxatives and especially enemas leads to dependency, increasing constipation and disruption of bowel biome. Plus, no known laxative except for ones targeting opioid receptors works by affecting any of multiple causes of constipation.

Please reconsider your tendency to hold on numbers and symptoms instead of looking for patterns and general picture. And, yes, those caregivers with their 35 hours of training can be explicitly ordered to ambulate patients and offer prune juice every morning and water during the day. You do not need an order to do that.

Another issue with poly-pharmacy is compliance. I think it is the rare 80 year old who takes all 15 pills as ordered. And, even when being cared for, complex medication regimens get done wrong.

I have never worked LTC. Given the staff PT ratio, I can't imagine that there is not a high error rate. I ave a theory that it is not unusual for Mrs Jones to get all 10 AM meds that should have been for Mrs Smith, and visa versa.

Specializes in ICU, LTACH, Internal Medicine.
Another issue with poly-pharmacy is compliance. I think it is the rare 80 year old who takes all 15 pills as ordered. And, even when being cared for, complex medication regimens get done wrong.

I have never worked LTC. Given the staff PT ratio, I can't imagine that there is not a high error rate. I ave a theory that it is not unusual for Mrs Jones to get all 10 AM meds that should have been for Mrs Smith, and visa versa.

I would rather say that compliance presents the same magnitude of problem as lack of it, only in different settings. Community dwellers can be woefully noncompliant about everything except effects which they feel for real (so, they are adamantly compliant with "ma' pain pills and nerve pills and sleep pills"). When the same person moves to acute care or in ECF, they suddenly become way more "compliant" then before - pretty frequently with bad results.

Another piece of story is medication regiment. Before meals, after meals, no grapefruit juice, no calcium within 2 h before and after, etc. Sometimes I wonder if the meds I give the patient play any role at all, or it is combined action of powers of nature, the God's will and patient's desire to get out of that room. Because the way they are administered, the meds just cannot work as predicted.

Specializes in Critical Care.

I'm pretty sure it's being old that kills them, not drugs...

Specializes in Cardio-Pulmonary; Med-Surg; Private Duty.
I stopped reading after Dr. Mercola was quoted. I'm sorry.

Glad I wasn't the only one!

Specializes in Geriatrics, Dialysis.

Questionable sources aside I can't disagree that polypharmacy is a huge issue. I work in LTC and have multiple residents on multiple meds to treat the same condition. Does anybody really 3 or 4 different blood pressure pills? Why on earth would an 80+ year old person need multiple meds to lower their cholesterol? I have a few residents that take 4 different diuretics. Most of them take multiple vitamins/supplements which I am pretty sure are doing little if any good.

I haven't even touched on the psychotropics and pain meds. That's because that's the one area we are seeing some improvement. Our opioid and benzo prescription numbers have gone way down. I've seen some push from pharmacy requesting reductions in psychotropics with moderate success.

Specializes in Med-Tele; ED; ICU.
Not a criticism of the article generally, but you might want to be careful about your sources. Dr. Joseph Mercola is a well-known quack, and I immediately lose interest in anything that mentions him as a source or authority.

(And, just for accuracy's sake, he's a DO, not an MD as you listed in your references.)

I was just preparing to write a response which would have parroted just what you've written.

Certainly polypharmacy is a huge issue among many of our older patients but beginning any discussion with references to Mercola saps credibility at the outset.

Specializes in Med-Tele; ED; ICU.
I think all Americans are overmedicated, not just the elderly. A big cause is direct to consumer advertising of drugs, initiated during the Reagan administration. "Just ask your doctor if Prozac is right for you!".

Occasionally I repost just for emphasis and this is so spot-on that it warrants repeating.

Specializes in Med-Tele; ED; ICU.
I work in a SNF. I have ONE patient on clonidine, lisinopril, hydralazine, metoprolol, Altace, and carvedilol!

When I asked if there was a way to reduce the amount of meds by increasing a few doses, they looked at me like I had 6 heads.

Six heads... one for each med! :-)

I'm pretty sure it's being old that kills them, not drugs...

That was my first thought. Everyone is damned if they do and damned if they don't.

I'm pretty sure it's being old that kills them, not drugs...

Inappropriate prescribing and polypharmacy can certainly accelerate the process, though.

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