It's different for everyone. I was willing to take whatever job was tossed my way, but I got a position in the ED right out of school, which is what I wanted. And I'm doing very well so far. I like the fast pace, and I like the fact that everyday is different. I have a classmate that is also in the same department as myself, and she cries almost everyday when she leaves. I generally look forward to work, she dreads it. On the flip side, I would freak out working in the NICU (my hospital does hire new grads into their NICU). Good luck!