I have not graduated yet. I have 5 weeks to go, and I'm counting down to my graduation on May 15th. (yay) However, I though that I would reply since you haven't had an answer yet. First of all, every nursing school and program are different, and that can have a lot to do with which subjects or classes are the most difficult. If you asked all of the students who started with me in my program which class was the most difficult, I know for a fact that over 90% of them would say Pediatrics. We lost about a quarter of our class that semester. I believe, however, that this is primarily due to the poor pediatric instructors that they have at my school. Of course, that doesn't apply to every instructor, but to the majority of them it does. My clinical instructor for Pedi was very good, but the classroom instructor wasn't. That makes a huge difference in nursing school. Another reason that Pedi was so difficult is because children are so different. Things can change so quickly with them. For me, the assessments seemed very different as well. By the time you get to pedi, you have already been working a few semesters with adults, so when I would walk into the room and look at their vital signs, I would almost feel a sense of panic. For the first few weeks, I had to keep reminding myself that these vitals were normal for kids. I was also terrified of doing something to hurt them. Of course, I don't have kids, so that may have been a factor for me. I thought the semester was emotionally difficult as well. We were at the children's hospital, and most of our clinical time was with children who either had cancer or heart defects. I don't think that every school does that, but mine did, and it was heartbreaking. I admire pedi nurses because I couldn't do that job for the life of me.
As for the easiest class, that is hard to answer. None of them have been easy. As far as content, I guess my first semester (Foundations) was the easiest. OB is the semester that I enjoyed the most, though. I loved it. I also loved mental health. This semester, my last one, has also been great because I can finally see things coming together. I have a phenomenal clinical instructor and great instructors for my classes. The classes have been overwhelming because of the amount of content that we have to cover. They are not difficult because the subject is so hard to understand, but they are difficult because you have no idea how you are going to manage to remember all of that material before the test rolls around. But, you gradually add to what you know and then you get to a point where you can see things coming together and you can remember some labs, drugs, etc. without having to run look at your book, pda, etc.
When it comes to clinicals, it is ALL about your clinical instructor. When you have a good instructor who truly cares whether you learn or not, then your clinical experiences shouldn't be so bad. However, if you have a bad clinical instructor, it can make your entire semester a living hell. Forunately, I have had really good instructors that I have been able to learn a lot from with the exception of my med/surg instructor who was a complete basket case. When you get into school, try not to rub elbows with your instructor. I know it is horrible, but I have really tried to go out of my way to be on the best of terms with every single one of my clinical instructors. I just don't need that added stress in school. I have witnessed several cases where a student has been tormented, belittled, and even harrassed by a clincial instructor, and it was sad. Sometimes there can be really big personality conflicts between students and instructors. Try not to let that happen. Just go to clinical with the expectation of learning the most you can. Don't complain, whine, or question your clinical instructor (unless it is something involving patient safety, of course). Just do whatever they say to do.
Anyway, I hope you have a really great experience in nursing school. I'm sure you will.