Morphine for Hospice Patients: What Nurses Need to Know

Morphine, when used in hospice care, is different than in the acute care setting. When making the transition to the role of hospice RN, it is important for nurses to understand the differences in use in order to provide education, quell myths and ensure comfort in an individual's final days.

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When moving from acute, inpatient nursing to home hospice, nurses have to reshape how they think about morphine. In acute care, there is an emphasis on minimizing narcotics, fear of creating addiction and adverse outcomes for patients after their hospital stay, and nerves around over-sedation and respiratory depression from narcotic use.

It is important for nurses to not let this bias transfer to in-home hospice care. Here, morphine and similar narcotics are commonly used to treat pain and shortness of breath during end of life. As patients, families and caregivers often have their own fears around morphine, the hospice nurse must provide education and support in using morphine in the home in order to maximize patient comfort during his or her final days. 

Why Morphine is Different in Hospice

Families report three primary fears around morphine used for at-home hospice: decreased communication, hastening death, and worries around addiction.

Morphine has a positive effect on communication in hospice patients

Try to imagine a time when you were in moderate to severe pain. Did you want to enjoy pleasant moments with loved ones, or withdraw into a ball on the floor? Were you your most open and kind self, or perhaps you became a bit snippy and mean? One of the common symptoms experienced near the end of life is moderate to often severe pain. 

Not managing an individual's pain at end-of-life can cause a person to feel angry and short-tempered, making it difficult for meaningful communication to take place, according to the National Institutes of Health. Ensuring someone is comfortable by using morphine, as prescribed by a physician, allows for improved communication between loved ones during final days. When we all think of our final moments, don't we wish for pain-free, love-filled final days or weeks, with shared memories and special moments. For hospice patients, appropriate use of morphine is often the ticket to just that.

In fact, in a study of 4,037 hospice patients using morphine for end-of-life symptoms, 85% saw little to no decline in communication. 

Morphine will not hasten death

We as nurses know that morphine can have terminal side effects like respiratory depression that can quicken an individual's death. However, multiple studies done with patients in at-home hospice care have shown no correlation between morphine use in the home and a quicker death. For one, the dosage is often lower in comparison to acute care settings, and the administration route is oral or intramucosal as opposed to intravenous. In-home dosing has low risk for respiratory harm, and in fact, often eases shortness of breath symptoms. 

In fact, a 2022 study showed that when an individual's pain was well controlled it benefitted sleep and appetite, improving quality of life and even extending survival. 

Hospice nurses can share this information with patients, families and caregivers to assure them they are not harming their loved ones, but rather improving their quality of life and allowing them more enjoyment in final days. When we are not in pain, doesn't food taste better, music sound better, and the voices of loved ones sweeter? And aren't these the things we hold onto life for?

Morphine will not cause addiction in end-of-life care

This one may seem straightforward, but it is still a common fear among individuals providing at-home hospice care. When receiving morphine for end-of-life symptoms, there is simply not enough time to become addicted.

One doctor stated, "at this point the most important thing is comfort.”

Nurse Responsibility

Nurses have a responsibility when providing end-of-life care to educate patients on morphine, quell fears and expel myths to ensure that patients are as comfortable as possible. As there is a lot of contradictory information about morphine use, the nurse must be well educated and confident to share this information with patients, families and caregivers to ensure optimal pain management and comfort during an individual's final days.


References

U.S. Department of Health and Human Services National Institute on Aging. Providing Care and Comfort at the End of Life.

Opiophobia in Palliative Care: Conquering the Last hill by Mamak Tahmasebi

Toward Evidence-Based Prescribing at End of Life: A Comparative Analysis of Sustained-Release Morphine, Oxycodone, and Transdermal Fentanyl, with Pain, Constipation, and Caregiver Interaction Outcomes in Hospice Patients 

Specializes in ambulatory care/ women's health/ pt education.

Totally agree that patient and family education is key when it comes to morphine for hospice patients. I used to tell folks that getting the patient comfortable was our primary objective for right now, which usually was a goal that everyone could agree on. I'd explain that once we got the pain under control, if they were still concerned about addiction/ dependence, we could definitely have a conversation about it. I only worked hospice for a year, but I never had anyone who wanted to discuss discontinuing morphine once they saw their loved one finally able to relax.

I am glad I came across this thread. I always struggle to know when the last moments of death are coming for my pts. 

Last night I had a pt who was comfort care. When I started my shift; she was EXTREMELY restless. Kept telling us to get her up, pulling at her gown, oxygen, and any tubes. The family was very hesitant on medications because they wanted her to be able to talk to them. I had to have a conversation with them about how her behaviors were signs of discomfort. The pt was verbalizing she was uncomfortable, as well.

They agreed. I was alternating 1mg Ativan and at first 2 mg IV Morphine so that she was getting something every 2 hrs. However, I had given the 2 mg IV Morphine twice and it just wasn't helping with her hard breathing. So I decided to give the 4 mg IV instead, which helped significantly.  

Repositioned her for a final time in the morning. Her breathing was definitely more labored and she was using her whole upper body to breathe.  I gave her the morphine again prior to repositioning as it was painful for her. I checked on her again about 20-30 minutes after giving the morphine and she was breathing easier and looked peaceful. I checked on her again and she had passed.

I struggle as I feel that the Morphine I gave is what ended it. My coworkers say it wasn't, that I gave her a peaceful death. However, was that actually end of life breathing that I had mistaken for discomfort?

Specializes in Hospice, Palliative Care.

Cheyene stokes and Kussmaul are among the common end of life breathing patterns, but nothing you wrote came across as excessive.  We are called to use critical judgement and you used yours.  Morphine and Ativan are not euthanizing agents; you did the right thing.

10 hours ago, pmabraham said:

Cheyene stokes and Kussmaul are among the common end of life breathing patterns, but nothing you wrote came across as excessive.  We are called to use critical judgement and you used yours.  Morphine and Ativan are not euthanizing agents; you did the right thing.

How are you able to determine when the last moments are? I haven't experienced a ton of deaths, but probably a hand full. I have found that it's always different for people. Some people will have those slow heavy shallow breathing patterns for days. 

My pt had that hard breathing I was explaining for maybe a couple of hours. She was declining very rapidly, though. Sunday at the start of my shift, she was very alert and talkative. Honestly, the most peaceful I'd seen her. I only gave her one dose of pain medicine (Oxy 10 mg) at the start of my shift and by the morning before I left; she was different. She had become extremely restless wanting to get up and pulling at stuff. 

Her family really didn't want her to get medication and she didn't either, so I was trying my best to give as least as possible. However, whenever she was awake on that last night; she was pulling at stuff and uncomfortable. 

Specializes in Hospice, Palliative Care.

It comes from experience and I'm not trying to be snarky.  I've articles on medium dot com that go over how to recognize terminal restlessness, when someone is within two weeks or less (does not include sudden death syndrome), etc. but the last time I tried to post such articles, the post was deleted for the reason of self-promotion even though I'm not trying to promote myself and I don't get any payments from medium.

1 hour ago, pmabraham said:

It comes from experience and I'm not trying to be snarky.  I've articles on medium dot com that go over how to recognize terminal restlessness, when someone is within two weeks or less (does not include sudden death syndrome), etc. but the last time I tried to post such articles, the post was deleted for the reason of self-promotion even though I'm not trying to promote myself and I don't get any payments from medium.

I don't find your post snarky at all. I'm literally trying to learn to become better at being able to recognize this. Yes, I have experienced the restlessness in all of my patients who were near death. I also have noticed their eyes change. They roll them in the back of their head more often. They also will stare around the room, stare at the ceiling, or just glare off in the corner. She was doing that about 48 hrs before her death. My grandpa would say that he saw all of his deceased siblings around his bed. When I asked my pt if she saw anything, she said she didn't. 

I truly believe looking back that that breathing before giving her that last dose of Morphine was agonal breathing. It took all of her upper body strength to get those breaths out. And I thought it was just her experiencing some air hunger. I feel bad because her sister was sleeping right next to her and I just wish I would have been able to recognize to be able to wake her sister up and say, "I don't think she's got much time left." Instead I had to wake up the sister and tell her she had passed. All I hope is that it was peaceful and I'm glad that she wasn't alone and had her sister near her even if she was asleep. 

Specializes in Have done it all!.
On 7/15/2022 at 6:52 AM, Mr. Murse said:

You have a valid point, but where's the line that separates "helping" a person with the process of dying and euthanasia? It's vague at best.

When we provide the meds for comfort & transition to death for anyone else’s timeline except the person that is dying.

we must be careful as healthcare providers to not help a patient transition because of a family member that just wants the patient to finally “go” or Because the hospital or facility needs a bed; If we start to do it for any other reason then to help the patient to truly have a peaceful death we are then entering into a whole other realm and that is pretty dangerous and unethical. I hope I’ve answered your question.

?❤️?? To all on this journey 

Specializes in CRNA, Finally retired.
Mr. Murse said:

?Never said that it did, my friend.

I also work at a hospital, where "1-2mg Morphine q5min PRN shortness of breath" is completely up to the nurse's discretion and it most certainly could hasten death with certain patients. You are in a different setting using different forms of the drug. As I said multiple times.......subjective.

I'm not disagreeing with you or accusing you, and I'm not even sure why this discussion has taken any kind of argumentative tone. My only point in chiming in at all was to point out that the issue is not as clean cut and simple as some of the post (including the OP) seemed to imply.

I'm sure you do your job well, and please believe I'm not accusing you and I understand quite well how it is "supposed" to work.

So what, exactly, is your point?  What did the OP say that made you think the article over simplified things?  Perhaps the issue could be de-simplified by adding multiple pages of information but here is not the place to post it.  I don't think anyone here in this thread has proposed that end of life decisions re: MSO4 dosing is easy.

Specializes in Mental Health, Gerontology, Palliative.
ForeverYoung018 said:

I struggle as I feel that the Morphine I gave is what ended it. My coworkers say it wasn't, that I gave her a peaceful death. However, was that actually end of life breathing that I had mistaken for discomfort? 

I once gave a patient 4 drops of clonazepam. They were restless and they died 10 minutes later. Peacefully

I had another patient who needed their bed clothes changed they died peacefully 20 minutes later

I had another patient who needed to be cleaned post bowel motion. They slipped away about 30 minutes later. 

Sometimes we will do an action or give a medication that results in speeding up someones dying process. Thats the operative words though, the person is already dying. 

Its good nursing care to be assessing our patients and basing our nursing care on that assessment. Your patient passed peacefully. You did a brilliant job. 

Specializes in Hospice, Palliative Care.

The 4 drops of clonazepam DID NOT speed up the dying process

Specializes in Mental Health, Gerontology, Palliative.
pmabraham said:

The 4 drops of clonazepam DID NOT speed up the dying process

Oh I know. 

I was trying to counter the narrative that nurses give all the scary drugs and that speeds up someones passsing. If there was any drug less likely to cause someones death it was liquid clonazepam. I think the total mg amount was 0.4mg (1 drop= 0.1mg)  I believe it was just enough to allow this patient to relax and let go. 

When mum went on a syringe driver, she was on 80mg morphine (previously 160mg meselon daily), with 20mg break through doses. She was getting break through doses of morphine   midazolam Q3 and it was keeping her comfortable. It didn't speed up the process.

IMO when a nurse infers that these drugs can kill its irresponsible. Sure, if prescribed/ used inappropriately. However our hospice doctors have a wealth of experience and don't do it.