why we can't give levonex IV ??!!

[SHHIYD]

^_^

i want to ask an question :-| so ..

this question in pharmacology :)

why we can't give levonex iv ??!!

thanks for all ..

[PetsToPeople]

As far as Google goes, it's all in how you use it. I must Google fifty times a day, when I have a question about something...now if I could only retain half of the stuff I look up and/or study!

[Esme12, ASN, BSN, RN]

(

esme12 )

thank you brother , now i now the reason , thanks for all :heartbeat

sister.... you did it yourself......and you are very welcome. :hug:

[punkydoodlesRN, BSN, RN]

Google is your friend........Let me google that for you

ok, how did you do that?? I need this for my classmates who always ask questions that could have been easily googled themselves!!!

[ashleyisawesome, BSN, RN]

just go to lmgtfy.com

i love using that! haha

[Esme12, ASN, BSN, RN]

It's actually a great search engine.....

[SHHIYD]

Sister.... You did it yourself......and you are very welcome. :hug:

^_^aha sister , today i discussed the question with my instructor and he was pleased from me Thank you sister :redbeathe and again thanks for all

[Esme12, ASN, BSN, RN]

Anytime friend. and Welcome to AN! :cheers:

[Music in My Heart]

Here's another way to look at it:

*Why* give Lovenox instead of plain heparin? *What* is Lovenox?

The answer to the latter is ultra low molecular weight heparin. Huh? What does that mean? Molecular weight? Huh? This isn't chemistry... or is it?

Here's the thing, we're not talking about small organic molecules here. We're talking about proteins... big, honking proteins... which are derived from animals (pigs, specifically). The issue with regular heparin is that the formulation is somewhat inconsistent (one of the difficulties in working with refined animal products rather than pure, synthesized drugs) and an individual's response to heparing is variable... hence, heparin requires regular (q6, q8, q12, q24) INR checking and is a high-risk medication requiring witness and verification prior to giving.

So what's so cool about Lovenox? It's still "heparin." The difference is that it's a highly distilled, refined formulation. That is, instead o having all of the various pieces of heparin that are present in the raw extract, only a certain subset of the various heparin molecules are present... which is why it's ultra low molecular weight... all of the big ones are gone. Hence, the response to the medication is much more predictable which is why it's (a) *not* a high risk medication, and (b) patients may self-administer at home.

However, Lovenox is *still* heparin... the dose and response curves, however, are all based on SQ injections, not IV... the manufacturer hasn't studied the proper way to give it IV... and frankly, that would defeat the entire benefit (and enormous relative cost) of Lovenox... so perhaps the simplest answer to your question is, "There's no benefit and it's much too expensive for that."

That said, you could do it but you'd need to monitor the patient very closely and there is a risk of an adverse effect simply because of the off-label administration.