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Discussion

GFR 150

I had a patient with a GFR of 150, but the BUN and creatinine was fine. Should I be concerned about anything? I asked my mentor and she was not too concerned about it. This is my first job, please advise. The patient is fine symptomatically.

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    • Guides

    Please look up normal values before you ask a mentor or even anyone here at allnurses. I would have had a perplexed look on my face if I were your mentor, no offense.

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    • Author

    Sorry Juan I panicked at my first job and I was hoping for some support.

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    • Experts

    By the way, I would love, love, love to have a GFR of 150, lol. Theoretically, with a GFR of 150 I'd be many years away from developing chronic kidney disease, which is a disease process that runs in my family.

    GFR of 150 = excellent renal function

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    • Author
    By the way, I would love, love, love to have a GFR of 150, lol. Theoretically, with a GFR of 150 I'd be many years away from developing chronic kidney disease, which is a disease process that runs in my family.

    GFR of 150 = excellent renal function

    lol i know GFR greater than 60 is normal. But I have never seen it this high. As a new grad / first job, validation from mentors is helpful. People forget how nervous they were 10-20 years ago when they first started and were full of doubts.

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    lol i know GFR greater than 60 is normal. But I have never seen it this high. As a new grad / first job, validation from mentors is helpful. People forget how nervous they were 10-20 years ago when they first started and were full of doubts.

    Actually ~90 is considered normal function, depending on age of course. If you're around 60, you already have declining function.

    The GFR is a calculation based on other numbers, not something that is measured specifically.

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    • Experts

    Here you go:

    Normal GFR — The glomerular filtration rate (GFR) is equal to the sum of the filtration rates in all of the functioning nephrons; thus, the GFR gives a rough measure of the number of functioning nephrons. The filtering units of the kidney, the glomeruli, filter approximately 180 liters per day (125 mL/min) of plasma. The normal value for GFR depends upon age, sex, and body size, and is approximately 130 and 120 mL/min/1.73 m2 for men and women, respectively, with considerable variation even among normal individuals [1].

    From UpToDate

    GFR is really just an estimate - its an equation based (depending on what formula you use) several factors. Its actually referred to as eGFR (estimated GFR)

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    There's nothing wrong w/a 150. Look up the 'normal' range (for this and any OTHER labs too).

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    The cause of TRULY elevated GFR: hyperperfusion + elevated circulating blood volume + anabolic state. Classic example is pregnancy.

    The cause of (usually) FALSE elevated GFR: hypermetabolic states with low protein consumption on patients with low muscle mass and good hydration level with recent weight loss (loss of body surface). Happens with untreated DM, uncontrolled hyperthyroid and manic disorder, for a few examples.

    High GFR does not automatically mean normal renal function. Patients with uncontrolled DM may have calculated GFR as high as 130+ (due to polydipsia, they drink a lot and flush out most of creatinine and BUN while kidney damage is going on, which is evident by urinary microalbumine being positive). Patients with untreated diabetes insipidus may have elevated GFR providing they are well hydrated (they often have some degree of anorexia).

    Providing calculation is correct, everything looks fine with kidneys, but I would most definitely wonder about the rest of the body. There got to be either elevated peripheral perfusion of quite an extent, decrease of protein consumption/metabolism indices, decrease of body surface area or any combination of them, and neither from this line looks good on the long run.

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    can i borrow some of that GFR

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    There's nothing wrong w/a 150. Look up the 'normal' range (for this and any OTHER labs too).

    Looks like I was wrong ... 150 is a bit high (normal seems to have an upper range of 120-130).

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    can i borrow some of that GFR

    Hey, I was standing here before you came!

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