Published Nov 8, 2006
ghost
43 Posts
Today Dilantin was held so a PEG tube could be stopped (Stop PEG for 1 hour, give Dilantin, restart PEG after 1 hour). The type of feed was "Nepro" (nutritional info, scroll down). How it was explained is that Dilantin clings to the "milk" in the tube feed and is excreted, thus not doing the body any good.
I looked up the ingredients for Nepro and it doensn't say anything about having milk. I also looked up Dilantin and that says it binds to "albumin."
Would you hold Dilantin if a patient was on tube feed (no matter the formula)?
What other drugs would you have to hold if a patient were on a tube feed?
Usage:
NEPRO is specifically designed and clinically shown to meet the needs and altered metabolism
of people on dialysis.
* In a study of Nepro as sole-source nutrition, people on dialysis had:
- Improved calcium-phosphorus product
- Decreased phosphate binder use
- Less constipation1
* For tube or oral feeding
* For supplemental or sole-source nutrition
Features:
# 1900 Cal (four 8-fl-oz cans) meets or exceeds 100% of the RDI for 18 key vitamins and minerals Low in vitamins A and D
# High in folic acid and vitamin B6
# Low in phosphorus and potassium
# Moderate protein content to replace protein lost during dialysis and to help prevent catabolism of lean body mass
# 3.7 g of FOS/8 fl oz (15.6 g/L). FOS are prebiotics that stimulate the growth of beneficial bacteria in the colon
# 3 flavors (8 fl oz)--Vanilla, Cherry Supreme, and Butter Pecan
# Low-residue
# Lactose- and gluten-free
# Kosher
Caloric Distribution
Per 8 fl oz
Per Liter
% Calories
Calories
475
2000
--
Protein, g
16.7
70
14.0
Fat, g
22.7
95.6
43.0
Carbohydrate, g*
52.8
222.7
Water, g†
166
699
*Includes 3.7 g/8 fl oz (15.6 g/L) of FOS.
†1 g water = 1 mL water = 1 cc water.
Analysis:
Hide details for Nutrient FactsNutrient Facts
8 fl oz
1000 mL
FAN (label number)7958-047642-01
Cal/mL2.002.00
Energy, Cal4752000
Protein, g16.770
% of total Calories
14.014.0
Fat, g22.795.6
43.043.0
Cholesterol, mg
Carbohydrate, g52.8222.7
Water, g*166699
Dietary Fiber, g3.715.6
L-carnitine, mg62261
Taurine, mg38160
m-Inositol, mg
* 1 g water = 1 mL water = 1 cc water.
Carbohydrate includes dietary fiber.
Dietary fiber: 3.7 g/8 fl oz (15.6 g/L) of FOS.
Hide details for VitaminsVitamins
Vitamin A, IU10004215
Vitamin D, IU2085
Vitamin E, IU1248
Vitamin K, mcg2085
Vitamin C, mg25105
Folic Acid, mcg2501055
Thiamin (Vitamin B1), mg0.62.6
Riboflavin (Vitamin B2), mg0.682.9
Vitamin B6, mg2.18.9
Vitamin B12, mcg2.411
Niacin, mg834
Choline, mg150635
Biotin, mcg120510
Pantothenic Acid, mg417
Includes 750 IU/8 fl oz (3160 IU/L) of vitamin A activity from 0.57 mg/8 fl oz (2.4 mg/L) of beta-carotene.
Hide details for MineralsMinerals
Sodium, mg (mEq)200 (8.7)845 (36.7)
Potassium, mg (mEq) 250 (6.4)1055 (27.1)
Chloride, mg (mEq) 240 (6.8)1010 (28.5)
Calcium, mg3251370
Phosphorus, mg165695
Magnesium, mg50215
Iodine, mcg38160
Manganese, mg1.35.3
Copper, mg0.52.1
Zinc, mg5.724
Iron, mg4.519
Selenium, mcg24105
Chromium, mcg
Molybdenum, mcg
Other Values
Density at 23°C, g/mL1.099
pH6.6
Osmolality, mosm/kg H2O665
Osmolarity, mosm/L446
Renal Solute Load, mosm/L491
Cal to meet 100% RDIs1900
mL to meet 100% RDIs947
Total Cal/g nitrogen179:1
Nonprotein Cal/g nitrogen154:1
Pepper The Cat, BSN, RN
1,787 Posts
We also schedule Dilantin doses around our PEG tube feedings. We have also been told that the milk or milk sustitute binds with the dilantin. I can't think of any other med we do this with.
NurseyBaby'05, BSN, RN
1,110 Posts
We also would have to hold our Dilantin re: tube feeding. One way we worked with it was to get the docs or PA's to order the Dilantin 300mg qhs instead of 100 mg tid. That way the pt's feeding was only held for 2-3 hours total, instead of 3x a day. We would also try to get orders for Prosource or another supplement to boost the calories and nutrition that they were taking in.
leslie :-D
11,191 Posts
i've never held fdgs w/dilantin.
our pharmacy told us that as long as we diluted it w/sterile water, dextrose 5% or 0.9% nacl, then flushed with minimum 20cc after administration, then nothing would stick to the tubing.
dilantin can interact w/milk products but absorption is so variable that many md's do not consider milk a huge contraindication.
there are too many other interferences w/dilantin, tube fdgs not being one of them.
i know nurses have always held fdgs for an hr.
but when i went to investigate why, the above, is what our pharmacy told us.
and further research came up with similiar findings.
leslie
DDRN4me
761 Posts
i have also mixed the dilantin with H20, and given with flushes both before and after. if the individual is not on a continuous feed it does help to schedule it when the feed is off. i have also found that crushing the chewables and diluting works better than the suspension, as it does not evenly distribute even when shaken..we found that dilantin levels drawn were quite inconsistent .
gitterbug
540 Posts
Always flushed prior to administration of Dilantin and after administration of drug with plain tap water per pharmacy and doctor's orders. We are a little more generous than 20 cc. In fact, may give a total of 100cc if patient has no respiratory problems, abdomen is nondistended, bowel sounds are positive x 4 quads, and tube placement was verified x 2 nurses. Most patients who get tube feedings do not get recommended H2O intake, so urine is concentrated, giving a little extra water when able just promotes better urine output.
absolutely!
i was just repeating what pharmacy told me- a minimum of 20cc.
what many don't understand that despite continuous feeds, many of these pts do not get enough free water so in the absence of any contraindications, and w/the recommendations of the rd and md, we've given 500cc h2o tid-qid.
Rnandsoccermom
172 Posts
Our docs routinely switch the Dilantin with Trileptal. The absorption rate is very unpredictable when giving dilantin and continuous tube feedings.
tatgirl
150 Posts
We have 2 residents on tube feeds that take Depakote, our orders are to stop the tube feed for 1 hour before and after giving the med, flush well while giving the med, and then restart feeding after 1 hour.
Wendy
LPN