What is wrong with these kids? (Mystery Diagnosis) - page 3

My area has recently seen 3 children at 2 separate facilities present with eerily similar and so far undiagnosed problems. Similar age group, but nothing else in common (different locations,... Read More

  1. Visit  LadyFree28 profile page
    1
    Could it be a rare reaction to like, a med???
    What are the pt's PMHx?

    One of my patients had excessive pulmonary bleeding, on oscillator, etc; improved when Drs figured out that valproic acid causes pulmonary bleeding...extremely RARE side effect...once patient was off the valproic acid and was switched to another anti-seizure med, she recovered. Immunology was involved; no immunologic deficit.
    anotherone likes this.
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  3. Visit  tewdles profile page
    1
    Interesting case...fever with no rash, unremarkable labs, progression of illness, and similar age/same gender.

    My guess is that there is some common denominator in here, if you find that you may solve the puzzle. Sounds like time is of the essence.
    anotherone likes this.
  4. Visit  ClearBlueOctoberSky profile page
    2
    With the demographics and similar presentation, is your local CDC office involved? They might have some insight as well.
    uRNmyway and anotherone like this.
  5. Visit  KelRN215 profile page
    2
    Quote from Franemtnurse
    Attachment 12442A lot of mysterious diseases are popping up from over use of antibiotics. This is a photo of my niece. She has had cancer twice, (notice her arm) This is from the removal of a cancerous tumor located in her arm pit. Her throat is still very sore, and she has had numorous tumors removed from her body. None of us know where this disease came from. My brother and sister-in-law were both genetically tested and were negative for the neurofiborblastosis that ravages her body. She just turned 16.
    Neurofibromatosis is a genetic disorder (autosomal dominant) that causes tumors to grow throughout the nervous system. It is not related to antibiotics at all. Fifty percent of cases are the result of a new genetic mutation and neither parent is affected. The other fifty percent are inherited from a parent with the disease.
    ashleyisawesome and Syrenia like this.
  6. Visit  JeanettePNP profile page
    1
    OP, what state are you in? Any exposure to wildlife, pets, insects? What about the soil, water, etc -- could this be environmental? You've got us all so curious and I hope you'll be back to post the denoument!
    anotherone likes this.
  7. Visit  Agrestigrl profile page
    0
    Any answers what could be causing?
  8. Visit  FleetFox profile page
    0
    A ten-year old boy presented with AMS in our ED today and all work-up was negative. He wasn't my patient, so I can't say what happened to him, although I believe he was admitted. Please let me know where you are located ASAP. You can message me. Thanks.
  9. Visit  DeLanaHarvickWannabe profile page
    0
    Fascinating and terrifying.

    Was the CSF checked for West Nile, by any chance? I know it's not really mosquito season but you never know...

    We had a lady with West Nile and everyone was baffled...diagnosis didn't come back until after she died, though.
  10. Visit  tewdles profile page
    2
    Any updates? My curiosity is surely peaked!
    anotherone and marycarney like this.
  11. Visit  Syrenia profile page
    0
    I was also wondering about West Nile.
  12. Visit  wellbeing12 profile page
    0
    Look at what they have been eating. May be due to pesticides/herbicides on fresh foods.

    Also check whether they have had immunizations recently.
  13. Visit  Ashley, PICU RN profile page
    2
    No PMH. All of these patients were healthy previous to their admission. Immunizations UTD on most, with no recent vaccinations in the past 6 months. CSF and blood was sent for a viral panel- I'm not sure if West Nile is included in these results but last time I checked the full results of the viral panel were still pending for the one patient left on our unit (the other was transferred at the request of the understandably frustrated parents searching for answers).

    The operating assumption is unspecified viral encephalitis. And actually, the patient on our unit is improving slowly and was actually extubated recently. The other three, to my knowledge, remain intubated. I suppose it's possible that we may never know exactly what caused this, which would be a rather anti-climactic end to this thread.

    Because of the similar symptoms, it seems like their has to be something in common, but so far nothing has been noted. Different locations, different schools, never met before, no similar contacts that we know about, no school trips, and we live in a fairly urban area so there is limited contact with exotic animals. Pets are an option, but in four separate households it just seems strange. Something environment you'd expect a more wide-spread outbreak.

    I'm in NJ and I'd rather not specify any more than that. To my knowledge the CDC is not involved yet, although there has been talk of bringing it to their attention.
    Esme12 and tewdles like this.
  14. Visit  marycarney profile page
    1
    Thanks for the update. I think about this thread often. It's just too coincidental with the demographics, don't you think?
    anotherone likes this.


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