Have a neighbor who called me this a.m. asking about how to cut a tablet that is once/day in half. The medication is an antidepressant - Pristiq. She said her pharmacist and doctor both told her she could if the dose she was originally prescribed continued to cause side effects because its not a "true" time released medication - that its made how it is to avoid the "dump" of the drug into the system so as to minimize side effects but is not dangerous in cutting in half as some other medications such as BP pills would be. She said he (not sure which one) told her it was like coated aspirin - there was no harm in cutting coated aspirin but the buffer effect on the stomach would not be the same.........
I told her I personally would not recommend cutting a medication in half that the manufacturer's info. specifically states not to and told her to contact her MD tomorrow.
In reality, I know medications like these are sometimes cut in half but I don't think its such a good idea. Am I wrong or dated in my knowledge on this?