I just accepted a PRN position at a hospital 50 miles (hour commute)from me. For me, at this time, the long days will be worth it as I will only work weekends which is what I wanted. My advice is to at least try the position - if you find it's too much and are able to drop to 2 days a week then do that or if it's just too much then you can find something else. Weather/traffic are variables that will change depending on unforeseen circumstances but most days you go will be "usual" traffic etc. And I rather, like a few others have posted, drive for a job I like than one I don't.