I am the wife of nurse, and currently a CNA. My husband and I have been married for 6 years, togeather for 10(we are 28y/o). I think it's compleatly unrealistlc to expect you to have an entire carrer with out any friends. You do need to be aware of your wifes feelings on this though, and you do need to be a bit more careful then you would if you were hanging with the guys. Hopefully your wife is understanding that just because your friends with a woman doesnt mean you're sleeping with her, or want to. It is easier for me, because my husband I work in the same hospital (he's ICU, I'm a float) I knew everyone he works with long before he did. They are facebook friends, they'll comment on his comments, pics of the kids, ocassionally write on a wall... He emails some coworkers who left the unit, mostly because they just finished CRNA school, and he was just accepted... They don't text eachother often, only "can you pick up a shift?" There were a few more during the possible strike here in MN last summer, but he won't spend forever on the phone. A few of them may have a beer after work, but the only person he hangs out with outside of work is honestly the only other male nurse on the floor. They happen to be the same age, and get along great, but not all you guys are so lucky. His friend though, ended up cutting off most of his friendships once he got married (but she's nuts, so no one should expect anyone to do that.) He chooses to keep a line drawn, because it makes him more comfortable, and because of that, we have never had a problem. You need to find what is a good balance for you and your wife, and not cross that line. "Work Wives" though, I do believe are not appropriate. even if this term is toung in cheek, I think a relationship intimate enough to use the term "wife" would make your real wife uncomfortable.