Speaking as someone who reviews approximately 10 - 15 nurse/physician resumes per day:
Don't bother with an objective statement, unless you're trying to go into an area radically different from where you've worked previously.
I don't give a crap what your hobbies are; I care about whether you're qualified for the job.
Please put specific dates (month/year) next to your previous job listings; you'd be surprised how many people don't do this either.
Don't use some weird cutesy font, colored paper, or a lot of graphics. Keep it simple and professional.
List your previous job experience in reverse chronological order, i.e., most recent first.
A cover letter is expected and necessary, but keep it brief.
3 short paragraphs.
1st paragraph: Hi I'm Bob and I'm looking for a travel job. I am particularly interested in your company because
: (excellent rep in the field, personal recommendation, intrigued by the brochure you sent, etc.) Do a little research and insert a fact to show you've done that reasearch. Nothing turns me off faster than spending 30 minutes talking to an applicant and having them finish by asking me something so basic about our company that they could've found it out on the first page of our website.
2nd paragraph: here are the highlights of my education/experience OR here's what I would like to draw your attention to on my CV that I feel would make me a good fit for this position.
3rd paragraph: I am available for interviews at/on (date & time). I am excited at the prospect of working for your fine organization (or similar blah blah) and I look forward to hearing from you soon.
Regards, Bob RN