Case Study: Fever

The following is a case involving a patient with fever. As the case evolves, I will present assessment findings, lab results, and diagnostic results in the hope of eliciting responses on how we would approach the care of this patient. Specialties Critical Case Study

Updated:  

The following is a case involving a young male who presents with fever associated with respiratory symptoms. This is based on a real case. The events leading to his hospitalization and his course in the hospital will be portrayed in an attempt to stimulate discussion on ways to approach his care not only from a nursing standpoint but also to understand the complexity of his care from the perspective of other disciplines who will be involved in his care particularly his medical management.

Background History

Rolando is a 19-year old college student who is the son of first-generation immigrants from the Philippines. His parents are divorced and he lives with his mother in a coastal town close to where he attends college. He decided to skip the fall semester and live with his father in California's Central Valley region to help him run a small business.

He presented to his family physician with complaints of productive cough for about 7 days and feeling warm and flushed. He said his phlegm looked white in color and not excessive. He appeared healthy and has no medical history other than having had his appendix removed at age 14. The physician prescribed him Azithromycin and cautioned him to seek further care if his symptoms do not improve. He recalls having some tests done at the clinic but was not sure what they were.

Three days later, Rolando was feeling worse. He feels he is warmer and may have a high fever, is having chest discomfort with coughing while not expectorating any phlegm, and is experiencing joint pains and muscle aches. He has no appetite and is feeling weaker. His father was concerned and brought him to the nearest ED at a community hospital setting.

Social History

His social history is notable for being a college student with an undecided major. He admits to drinking alcohol occasionally but denies binge drinking, he does not smoke, he admits to having smoked marijuana in the past but not recently. He has a girlfriend in college and is sexually active.

You are Rolando's first contact in the ED as the triage nurse.

After gathering the above, you obtained the following data

  • Subjective complaints: "feeling warm, headache, little short of breath".
  • Vital Signs: Temperature 39 C, HR 112, RR 32, BP 110/65, O2Sat 88% on room air
  • Neuro: AOx3, moving all extremities, pupils equal and reactive.
  • CV: EKG showed Sinus Tachycardia with no ST changes, no murmurs were heard on auscultation, no edema in extremities.
  • Pulm: Harsh breath sounds bilaterally but no accessory muscle use. He does breathe fast as you noted in his respiratory rate.
  • Skin: Warm and flushed, you notice what looks like a red rash in his bilateral shins.
  • Remainder of the system exam is WNL.

How would you triage Rolando and what tests would you expect to be done in his case?

What would you tell the next ED nurse who will take care of Rolando once you determined the appropriate ED treatment area he should be treated at?

What concerns do you have about what is likely the reason for his symptoms?

Titrate the propofol down and/or go wide open on the .9 saline to raise the bp? Seems the propofol rate is too high or increased too quickly.

Monitor sedation level, allergies

Ooooooo, this is interesting.

In our ED, CRNA's are the only ones besides the MD's that can intubate in the ED setting.

Because the patient could actively participate in the initial conversation regarding intubation, and typically a young, healthy person, then I would have suspected a bit more propofol was used to sedate to the point of intubation. To decrease the propofol would be tricky, as there would have to be a balance so patient is sedated but not over sedated. Patient is 5'8", however, what kg is patient?

I would decrease the drip a bit, see if the BP comes up and PR comes down a bit.

Changes in vitals such as this would point to a possibility that patient is going into shock, with a low BP and increased pulse rate. Which may not have a thing to do with the intubation, and more to do with the infectious process.

Stat pulmonary consult, to get a start on broad scope antibiotics to attempt to turn this around.

Not an ED nurse.. But I'll give this a shot. There are certain things that are "glaring" at me when I read this.

1) Just moved to Central Valley, new job with father in a "small business" (that's a clue), Philipino decent

2) Mild respiratory distress, Joint pain, BILATERAL SHIN RASH

After the first post, it's still hard to know what could be going on but I knew those facts were important

Second post - Things that stood out

1) Chest X-ray abnormal, you stated it was consistent with bacterial infx

2) Elevated WBC - Infectious process going on

3) Increasing respiratory distress only after 1 hour under your care

Patient is going from mild respiratory distress to acute, he has Chest X-ray that is consistent with bacterial infx. Now at this point it could still be anything, but I don't think pneumonia, influenza has this kind of presentation especially with a young healthy man. The difference here is that he just moved to Central Valley with his father and is working at his business. Why was this screaming at me? I don't know. I cheated a little and googled Central Valley, Flu, rash, joint pain or some kind of combo, and Valley Fever popped up.

Valley fever is caused by a fungus called Coccidioides immitis or Coccidioides posadasii that thrive in desert soils. The case presentation is consistent with Valley Fever: Rash, Fever, Joint pain, chest pain, abnormal chest x-ray etc. I'm willing to bet the father either works in construction or landscaping that has exposed the patient to this fungus.

Culture would need to be obtained to confirm diagnosis, IV antifungals should be started after positive culture returns, IV fluids, tx of symptoms, monitor pain levels.

As for the third post, pre intubation the patient was in respiratory distress and had increased RR to compensate for his inadequate pulmonary function. Post intubation the patient's ventilations are set to 20 so his RR will read 20 (I think?), his HR is lower because he is no longer in distress and/or because the sedating effects of propofol. I believe propofol is causing the b/p to drop although IMMediately post intubation I do not think it is a reason for alarm. Monitor patient vital signs q5min for at least 30mins and if b/p does not go up then consider titrating propofol.

I don't think anyone should be surprised that Rolando dropped his pressure. Like I said earlier he has been feeling sick for a while, tachypneic, probably is infected and just got sedated. Run those fluids in! Titrate down propofol as tolerated. Once patient's pressure is up a little roll him on over to the ICU. If he doesn't respond to fluid resuscitation he'll probably get lined for pressors and to check a CVP. An a-line would be good for labile blood pressures and frequent ABGs. Now that he has an ETT maybe we could do a bedside bronch once he stabilizes. He should be getting broad spectrum antibiotics at this point and coverage for fungal source (fluconazole?).

juan de la cruz said:
Rolando was appropriately triaged as emergent and was placed on Airborne Precautions in negative room pressure. The triage nurse appropriately secured an order for high flow nasal cannula. You are now his nurse in the ED.

Orders were for:

Respiratory Viral Panel, Sputum bacterial and gram stain, Legionella serum Ab, Pneumococcal serum Ag, Sputum for AFB. You were able to send all the appropriate specimens for these tests.

You were also asked to obtain ABG with lactate, CBC, Basic Metabolic Panel, and Coagulation Studies. Blood cultures were ordered. UA with tox screen was also ordered.

A portable CXR was obtained.

Available labs revealed:

ABG:

Ph 7.40 pCO2 37 pO2 56 HCO2 22 BE 0 Sat 90% Lactate 2.5 on HF at 100% FiO2

CBC:

WBC 18,000 Hgb 16 Hct 48 Plt 300 (+) Eosinophilia

BMP:

Na: 140 K 4.0 Cl 100 CO2 22 BUN 15 Crea 0.5 Gluc 87

Coags:

PT 14 INR 1.1 PTT 23

UA:

negative for UTI or drugs

CXR:

Rolando is working a bit harder to breathe after 1 hour of being under your care. What would you anticipate next?

Central Valley, huh? Hypoxia without hypercarbia? Valley fever.

GrnTea said:
Central Valley, huh? Hypoxia without hypercarbia? Valley fever.

I tried to edit but got frozen out somehow. I meant to continue:

I didn't read any other comments before posting, I swear. I lived in CA and saw this presentation often. I'm thinking this poor boy buys himself a lot of sedation and an FIO2 of 1.0 and all the PEEP he can handle to get his FIO2 down and his PaO2 up. He gets amphoterrible or whatever else is specific for mycoses these days. If he is lucky he does not end up in a box.

Specializes in Oncology.

I've never looked much into Valley Fever before, but researching it now, it seems this case fits the bill.

Nurse's role in RSI: Monitor heart rate, oxygenation, respiratory rate, and s/sx of pain, educate and reassure patient throughout procedure, ensure adequate IV access, administer drugs for sedation, paralysis, and to maintain BP, ensure necessary orders are ordered both for during RSI and to maintain patient stability and comfort afterwards (continued sedation, eye drops, fluids, blood pressure support, lab work), place foley and NG tube shortly after intubation if not already done.

The drop in blood pressure is related to sedation from the propofol. Increased oxygenation and respiratory rate of 20 related to vent settings. Drop in HR related to relaxation, and better oxygenation. I'm okay with the BP for now, but he may need increased fluids, decreased propofol, or a pressor if it drops further.

Treatment at this point likely involves transfer to ICU and antifungal therapy, likely with amphotericin as he is critically ill.

Specializes in Oncology.

So does he have Vally fever? I L O V E these threads!!! So fun (nerd alert).

danceyrun said:
So does he have Vally fever? I L O V E these threads! So fun (nerd alert).

I am with you on that!!

Specializes in ICU-my whole life!!.

Just a question to the OP, did an RN administer the propofol? Or a CRNA? I agree with the rest of the posts/comments already posted. Good case study. Has my old brain gears spinning...

Specializes in ICU-my whole life!!.

Any updates?

Specializes in Neuro ICU and Med Surg.

Update please.