Turning off lipids in infected babies

Do you all do this? My current hospital does, but I haven't been able to find any good litterature on it.

[Gompers, BSN, RN]

Do you all do this? My current hospital does, but I haven't been able to find any good litterature on it.

The only infection we turn lipids off with is the fungus Melessesia Pachydermitis (I think I spelled it right, but forgive me it's early in the morning). There was a copy of a printed article in the baby's chart that mentioned it being carried through the bloodstream by lipids, so they were DC'ed on the baby until he had clear cultures.

[BittyBabyGrower, MSN, RN]

Yes we do...it has something to do with leukocytes. I'll have to see if I can find the info.

[dawngloves, BSN, RN]

Really? Never heard of this.

[MsJessikia]

havent heard of them doing it at my hospita.... but im very intrigued????

[BittyBabyGrower, MSN, RN]

I found my short hand notes LOL They are from an article in the late 90's. Some organisms such as E.Coli and S. Aureus and some fungi make a "slime", esp around catheter sites and this keeps the poly leukocytes from being able to engulf the organisms. Lipids add to this "slime"...the organism likes lipids because it helps to make the slime for impermeable.

[premies_4_40yrs]

Do you all do this? My current hospital does, but I haven't been able to find any good litterature on it.

Never heard of this, but I'm going to inquire when I go back to work on Tuesday. Interesting idea!

[nekhismom]

well, that could certianly explain some of what's been going on with some of our kids. We run lipids 24 hrs and don't d/c for infections.

Other hospitals run lipids 18 hours...anybody know if the rationale for that is related to infection as mentioned here?

[BittyBabyGrower, MSN, RN]

I don't think so. We run our lipids over 4-24 hours, depending on how many grams/k/day they are getting. I want to say that for 20% IL, they usually run at 2cal/ml, rate <.12 gm i don know if that varies from institution to but is how we figure ours.>

[nekhismom]

Thanks, bittybabygrower!

[fergus51]

Thanks for the info. Bitty, do you happen to remember the title or the author of that article? The reason I'm asking is one of the docs insists there have been no "good" studies showing it's necessary and it causes a big disagreement whenever he's on cause everyone else seems to think the babies will explode if we don't do it right away, all the time, every time we suspect any infection.

[BittyBabyGrower, MSN, RN]

From what I can deciper LOL I think it is from Pediatric Journal of Medicine, but I can't read my year. Let me see if I can ferret it out at work when I go back later this week.