Last week a 30 yo female came in with RUQ pain. She looked shaky and pale. I hook her up to the monitor and her pulse is 180, BP 180/100. Hmmmm...that's not good, so my counterpart is starting an IV and I get her history--she has Graves Disease. As a new grad, I thought, hmmmm, I remember reading about this, crap, she is in thyroid storm. So I run to get the Doc. Well, we gave adenocard, metropolol (IV and PO eventually), cardizem over the course of an hour or more and she was getting worse, pulse up to 210. I kept thinking why don't we give her something for her thyroid--PTU, or whatever, but who am I to state the seemingly obvious as a new grad.
I gave her 2 mg of propranolol very slow IVP, with no change, and repeat the dose 20 minutes later per orders. Well after about 3 minutes she starts to vomit, then her pressure drops to 80/40 and pulse down to 40! We gave her a little bit of Atropine and started a Dopamine drip, NOT WORKING, she looks like sh** and her pulse and pressure kept dropping. Maybe the PO metropolol hit her... I don't know. I have never given a lot of these drugs before so I am wreck at this point--a nurse was helping and the doc was at the bedside most the time, but still! We start to bolus her and turn her on her head and all that, then she gets short of breath and her O2 starts dropping. The doc thought maybe it's a PE so we whisk her away to CT where they discover she has fluid in her lungs and her heart is large.
We ended up putting her on Bipap and got her pressure and pulse up a little before we sent her to ICU. (after we dumped 3 liters in to get her pressure up--this was before the SOB started though)
So, have any of you ever cared for a patiet in thyroid storm? The doctor said this is not thyroid storm. Her T4 was insanely high but her TSH nonexistent. I got home and looked it up and thyroid storm causes CHF eventually. That just has to be what happened. Why didn't we give her PTU? Why did she bottom out all of a sudden when we had waited in between all the doses? Thought this might be a better learning experience if I had some more input.