Pantoprazole IV question!

Nurses General Nursing

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How long does your hospital run Pantoloc (Pantoprazole) IV for? The new hosp I work at runs it ver 5 hours! 100mL @ 20cc/hr Its nuts, The other 2 hsopitals I worked at just ran it over 30-60 mins! Any imput? Or rationale as to why this may be? I am gonna ask pharmacy on my next day shift. Thanks all!

Specializes in ER.

We do the same for our GI bleeds as begalli...80mg bolus, 8mg/hr...we will do it with Octreotide but only if its esophageal varicies...

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Pantoloc is only stable for 6 hrs I believe after it's been reconstituted. We mix a 40mg vial in 100cc NaCl. Each bag runs at 20cc/hr (over 5 hrs) to be safe then a new bag is hung. That's if the Dr orders a continuous infusion.

If it's ordered OD, it's mixed in a 20cc syringe which is allowed to run at a maximum rate of 100cc/hr. No filters here either.

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We went from running over an hour with a filter, to running over 15 minutes with a filter, then over 15 minutes, then IV push over 2 minutes with a filter, and now there's no filter and we IV push over 2 minutes. We don't have to refrigerate it anymore either. All this over about a year!! LOL

:)

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Specializes in Critical Care/ICU.
Pantoloc is only stable for 6 hrs I believe after it's been reconstituted.

12 hours. We change our drip bags q shift.

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Specializes in Acute Medicine/ Palliative.

OK wow thanks for all the replies. Yes the pt is a GI bleed, no varicies.

She has running NS c 20 KCL @100 aswell...so, what about the K in the NS? is this ok to be ran (pantoprazole) at the Y site concurrently with the Primary solution? Should the primary be running at the same time so the pt is recieving the NS c 20 at the same time as the panto? I was so confused at the way it was all set up...I will look into it again tomorrow (back for 4) and I will get back to you all. As far as I recall from school, panto is not compatable with K... I looked it up in the parentral maual and it is not clear.

Thanks all for the help and discussion! Love it!

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Specializes in ER.
OK wow thanks for all the replies. Yes the pt is a GI bleed, no varicies.

She has running NS c 20 KCL @100 aswell...so, what about the K in the NS? is this ok to be ran (pantoprazole) at the Y site concurrently with the Primary solution? Should the primary be running at the same time so the pt is recieving the NS c 20 at the same time as the panto? I was so confused at the way it was all set up...I will look into it again tomorrow (back for 4) and I will get back to you all. As far as I recall from school, panto is not compatable with K... I looked it up in the parentral maual and it is not clear.

Thanks all for the help and discussion! Love it!

Well considering that it is stable for use with lactated ringers, and LR has potassium in it. I would say yes, its okay, however, I could not find anything definitive to say either way.

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Specializes in Telemetry, ICU, Resource Pool, Dialysis.
Well considering that it is stable for use with lactated ringers, and LR has potassium in it. I would say yes, its okay, however, I could not find anything definitive to say either way.

Our pharmacist says don't worry about compatability issues with small amts of K added to fluids - it doesn't really matter because it's so dilute. K gtts are another story.

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Specializes in ER.
Our pharmacist says don't worry about compatability issues with small amts of K added to fluids - it doesn't really matter because it's so dilute. K gtts are another story.

Okay, found it...according to medscape multi-drug interaction checker...there was no interactions found between protonix IV and potassium chloride IV. It did not give a specific amount of potassium as a choice, however it did differentiate between iv Kcl, and Nss w/kcl, and D5 KCL etc...

http://www.medscape.com/druginfo/druginterchecker?src=google

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I cannot recall the dosage right now, but we have Protonix drips that run either continuously or over many hours for active GI bleeders in the ICU.

So how many mg is the patient getting over these 5 hours? If it's only the usual prophylactic dose of 40mg, then that doesn't sound quite right.

The active GIBers from what I have seen are typically 10-20mg/hr.

We give prophylactic 40mg IVP over two minutes.

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Soooo, I was visiting a friend in the hospital last night and she was there for severe anemia s/p an EGD the day prior so suspect a bleed from the bx done then. When I visited she had RBC's at 100/hr NS at 80/hr and a Protonix Gtt at 10/hr ALL GOING INTO THE SAME IV SITE. No central line or picc, just a regular PIV. No adverse affects that I'm aware of, anyone heard of this practice??:confused:

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