ECMO - Will We Have Sufficient Capacity for the Fall/Winter Flu Season?

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I ask this question because twice this week that I am reading of critical swine flu patients having to be transferred to other facilities for treatment with ECMO. I am wondering how many critical cases would require this extreme level of care.

I would not think that many would but, if many people come down with this flu this fall, that would likely increase the number of critical cases, some of which may need this procedure. I am curious about what our capacity is to do this in the US. Surely only the biggest hospitals would be able to treat these cases.

The UK is having quite a strong outbreak of swine flu right now, and it is summer there. Australia, on the other hand, is in the middle of their winter flu season. It is hard to make comparisons between the two different places. At any rate, here is the first report that I came across:

http://www.dailymail.co.uk/news/article-1201825/First-picture-pregnant-woman-rushed-Sweden-swine-flu-virus-threatens-overwhelm-intensive-care-wards.html;jsessionid=C985E455C9FE4EC6E64190D88CC04A4E

This article describes the transfer of a Scottish woman to a four bed ECMO unit in Sweden. The Swedes came and got her by private jet. Strangely enough, this was the link for a different article on the same case a day ago, but has since been replaced by this latest article. I have no faith that it won't be replaced by yet another topic very soon so I will paste the pertinent info.

www.dailymail.co.uk said:

Ms Pentleton is monitored 24-hours a day by an array of equipment and a team of specialists.

She arrived on Thursday evening after Swedish doctors chartered a private jet to fly the two hours to Scotland to pick her up.

Crister Classon, a spokesman for the hospital, said: 'We are happy to help Britain or any other country if they run out of beds.

'It is a normal procedure to help other countries when they need it.

'We have only four beds and we currently have two swine flu patients in them, so there there are presently only two spare beds.'

It is thought a second British patient may be transferred to the unit.

The hospital's Dr Palle Palmer explained that the ECMO machine - similar to a heart and lung machine - was used to 'buy time' for patients. He said people could be kept on the machine for up to two months, but added that most patients did not need ECMO treatment for that long. He said: 'Normally it takes about two weeks, that's the normal treatment. But it is possible to run it for longer.

The Glenfield Hospital in Leicester, where doctors had hoped to treat Miss Pentleton, has the first designated ECMO unit for adults in the UK. But because it was full - with two of its five machines already being used by swine flu patients- medics turned to Stockholm.

ECMO treatment has only recently been accepted into mainstream NHS practice, being regarded as experimental in adults until the completion of a trial six months ago. Seriously sick children have been successfully treated for some time.

Best chance: Scottish health secretary Nicola Sturgeon said it was vital Miss Pentleton was transferred to Sweden

Consultant cardio-thoracic surgeon Mr Richard Firmin director of the ECMO unit in Leicester, said an average of 100 patients a year are treated there and beds could be expanded to 10 if absolutely necessary.

Patients are attached to an ECMO machine while their lungs recover from a variety of conditions, including viral infections and trauma. It involves circulating the patient's blood outside the body and adding oxygen to it artificially, Mr Firmin said 'The circuit is basically an external lung. Anybody who ends up with ECMO is somebody who is at the very severest end of lung failure.'

Patients may need treatment for two to eight weeks, at a cost of £55,000 to £105,000 per patient. Professor David Menon, an intensive care specialist at Cambridge University, said a small minority of swine flu victims who need intensive care have suffered a direct viral attack on their lungs, rather than a secondary infection. The condition called pneumonitis involves destruction of lung tissue.

Specializes in CVICU.

An update on our 2 ECMO patients:

20-year-old male is doing better. Decannulated on Monday. Now on 30% FiO2 by vent. Will probably need a trach unless they can get him off in the next couple of days. He's making purposeful movements but not following commands yet (was on paralytics and a lot of benzo sedation throughout ECMO course). He's still needing some sedation for vent dyssynchrony, so I think he will probably wake up once he's either trached or extubated.

Old heart tx patient also decannulated on Monday. He's now on 40% FiO2 and 10 of PEEP, and I was unable to wean it. He already had ESRD and he's been on SLED and continues to be on SLED, and needs pressor support. During ECMO, the patient's cannulas cavitated so badly with positioning that staff were unable to turn the patient during therapy... he's got a huge decub now :( I'd say his chances of making it out of the hospital are very slim.

We currently have 4 H1N1 confirmed and 1 suspicious (awaiting PCR) on vents on our 12 bed CVICU. All other ICU beds are full and the brass are allowing overtime and actually putting some of the less sick ICU patients in the PACU while this is going on. We have about 50 adult ICU beds, not including places that can take "overflow" vents such as Burn.

Now I have flu-like symptoms, so I won't know what's going on until next week.

On a side-note, I probably didn't get my illness from the hospital where I wear proper PPE. I think I got it from one of the various Halloween parties I attended over the weekend as it had been six days since I was last at work and developed symptoms.

Specializes in NICU, PICU, PCVICU and peds oncology.

Well, I've just returned from our war zone. Current count: 16 bed unit, 6 confirmed H1N1, 3 suspected, 2 on ECMO/CRRT, 2 on HFOV and 1 (s/p heart transplant) on high-flow nasal cannula, 1 still intubated but off isolation now after treatment with oseltamivir and 1 ECMO death. The oldest is the no-longer-isolated at 16 years, the youngest is 4 months. The younger of our ECMOs is unlikely to survive as there's an MRSA sepsis/vasculitis superimposed. My patient today is 3, on HFOV and requiring continuous neuromuscular blockade. Also has a really nasty extravasation injury that will probably need grafting.

We also have an infant on ECMO for cardiovascular reasons who has been on for 8 weeks, also s/p heart transplant (great example of what not to do). Our adult unit has 1 flu ECMO and 1 CV ECMO. We're sharing backup circuits now and there's a rumor afoot that our mothballed former CVICU will be opened as a combined adult/peds pandemic ECMO unit on the weekend. I hope they don't plan to cancel my vacation that's coming up the 12th to the 23rd!!

Specializes in Clinical Research, Outpt Women's Health.

Thanks for the reports. I wish the vaccine was more readily available. I have 2 friends in Canada and both of them have children home from college with the flu.

Specializes in CTICU.

It's started up in earnest for us too - currently have 3 adults on ECMO for H1N1, and just got another readmitted (was pregnant but crashed and had emergency C-section).

I am getting my shot on Monday if they don't run out.

Specializes in NICU, PICU, PCVICU and peds oncology.

When I left this morning we had 7 in total, five ventilated with the same two on ECMO. Our youngest today is 3 months old. Two are formally DNRs now but NOT the two on ECMO. We transferred one to another PICU in another city.

I was thrown a curveball yesterday when my brain-injured and immune-compromised son's day program called to tell me he was symptomatic and had to be picked up ASAP. Sudden onset fever and cough... classic. (He'd been vaccinated on October 27th, but this isn't the first time that failed us - he got chicken pox many years ago despite having been given VZIG within the recommended time frame.) He didn't seem all that sick to PICU-Mom so we didn't waste our time sitting in the GP's office. I ran it all past our intensivist when I went to work and came home this morning with a 5 day course of Tamiflu for him. He still doesn't seem all that sick, thank God. He can't go back to his program until his symptoms are gone, so his dad is taking time off so I can go to work and look after other people's sick kids. Sigh. (My patient's mom told me this morning that I'm "wonderful". Aren't I? Sometimes I wonder.)

Specializes in CTICU.

Hope your son is all better soon, Jan.

Specializes in NICU, PICU, PCVICU and peds oncology.

Thanks. I'm sure he will be.

Specializes in Too many to list.
Hope your son is all better soon, Jan.

Ditto that, and yes you are wonderful.

Specializes in NICU, PICU, PCVICU and peds oncology.

:omy: I'm blushing...

I thought this may be of interest - if you have not already seen it. It is a lecture by Dr Paul Roberts from Sydney Australia about their experiences with ECMO and adult H1N1(2009) cases over the flu season. He looks at equipment, transport with ECMO by ambulance, helicopter and plane. He also covers a combined Au/NZ paper which is going through peer review.

Hat tips to Anne and Sally at FluTrackers.

I am not a HCW I just have an interest in the epidemiology of the pandemic and what can be learnt from how we deal with it. In the UK I think we have 5 adult ECMO machines in one center and suspect we could have used a lot more by the end of our flu season.

Specializes in NICU, PICU, PCVICU and peds oncology.

Thanks for the link, JJackson.

We successfully decannulated one of our patients yesterday. We still have one on ECMO and one on HFOV. I don't think we've peaked yet though.

Specializes in Too many to list.

Cleveland, Ohio

http://abcnews.go.com/Health/SwineFluNews/h1n1-victims-healthy-deaths-door-week/story?id=9054126

Bradbury and Savitts were airlifted from smaller hospitals to Case Medical Center, where they arrived in critical condition, barely able to breathe.

Dr. Arie Blitz, a surgeon and medical professor, treated both men. He said when Bradbury arrived, his vital organs were failing.

"He was pretty much dead when he came in," Blitz said. "He developed something that I have never seen before in medicine ... four things at once. ... He had H1N1 flu. He developed a big pulmonary embolism, which is a clot that was sent off to the lung. He had a heart attack, and he had a stroke all at the same time."

Blitz told Bradbury's wife that her husband had a 1 percent chance of survival. "They pretty much informed all of us that he wasn't going to survive," Murton-Bradbury said. "One of the vascular surgeons came out and gave me his wedding ring, which was terrible, to say the least."

Savitts wasn't doing much better. His lungs were so badly damaged, according to Blitz, that it was as if they'd been torn to pieces. Both men were beyond the help of ventilators, so doctors performed emergency surgery, called extracorporeal membrane oxygenation, or ECMO.

(hat tip pfi/homebody)

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