Drug calculation

Mandychelle79, ASN, RN · Mar 10, 2017

What were you looking for in the first place? With the given information it's not a calculation problem

foleyu · Mar 10, 2017

I was told me mix it with 10mls of water for injections by a staff member. Without this piece of information.. how do I get to knowing its 10mls by a simple calculation?

Thank you for reply.

HeySis, BSN, RN · Mar 10, 2017

This can be done by solving for x

#1 set up the equation with what you know and use x for what you need to find

5000u = 25000u

2ml = (x)ml

#2 cross multiply

5000(x) = 25000(2)

#3 multiply

5000x = 50000

#4 dived both sides to get x alone

5000x = 50000

5000 = 5000

#5

x= 10ml

Every time I save it keeps getting rid of spaces so things aren't lining up!!! I'll try placing equal signs on bottom and top of equation and see if that helps.

NotMyProblem MSN, ASN, BSN, MSN, LPN, RN · Mar 10, 2017

I was told me mix it with 10mls of water for injections by a staff member. Without this piece of information.. how do I get to knowing its 10mls by a simple calculation?
Thank you for reply.

If you started out with a powder, the staff member most likely obtained the 10ml diluent instruction from the insert that accompanied the medication. After doing this once or twice, it becomes a given.

The calculation from a the previous poster is on point. But the insert in the package tells you how much of what kind of diluent is needed to give you the maximum amount of medication. Then you'd proceed to draw up the ordered amount after performing the calculation.

Anonymous865 · Mar 11, 2017

Urakinase:
I want to give 5000units in 2 mls.
I have 25,000 units in powder form.
I know you mix the powder ampule with 10mls water for injections and draw off 2mls to get your 5,000units in 2 mls.
What is the actual calculation?

I'm curious if this is just a theoretical math question for a class or if this is for an actual patient?

You really need to read the package insert or the drug manufacturer's prescribing information.

If you did, you would be really questioning the information you have above.

Everything I find says that Urakinase is supplied as a white powder in a vial containing 250,000 IU not the 25,000 units you have above.

The manufacturer states to add 5ml of sterile water to reconstitute it. Do not shake the vial just roll it to minimize formation of filaments.

Then you dilute it with either 0.9% sodium chloride or 5% dextrose.

Even the dose of 5000 units sounds off. The recommended dose is 4,400 IU per Kg given over 10mins. Then a rate of 4,400 IU per Kg per hour.

Guest219794 · Mar 11, 2017

I was told me mix it with 10mls of water for injections by a staff member. Without this piece of information.. how do I get to knowing its 10mls by a simple calculation?
Thank you for reply.

I am not sure that I , or anybody actually understands your question.

But, if you start with 25,000 u, and want 5,000 u, give 1/5 of your solution after mixing.

I have never mixed it, but if you add anything to 10 mls, the end product will generally be more than 10 mls. Assuming that's is correct, 2 mls will be less than 5,000 u.

Calculation wise- assuming you actually have 25,000 u in 10 ml:

What you want, divided by what you have, times volume.

Or:

5000 / 25000 X 2 = 2 ml.

Bt, how about a little context here- are you a student, a nurse......????

chare · Mar 11, 2017

[...]
5000 / 25000 X 2 = 2 ml.
[...]

This should be 5000 Ã· 25000 Ã— 10 = 2