Jump to content

Diluting propofol in lidocaine

Medications   (313 Views 8 Comments)
by nurs1ng nurs1ng (Member)

6,191 Visitors; 149 Posts

advertisement

Putting 5 cc of 1% propofol into a 10 ml syringe and mixing it with 5 cc 1% lidocaine... what would that give me X mg/ml of propofol? Just wanna make sure I have my calculations right. Any help would be appreciated

Share this post


Link to post
Share on other sites

4 Followers; 17,976 Visitors; 2,757 Posts

All you need to figure out is how many milligrams/ml of Propofol are in a 1% solution. It matters not how you dilute it. The dose won’t change only the concentration will. 

Share this post


Link to post
Share on other sites

6,191 Visitors; 149 Posts

1 hour ago, Wuzzie said:

All you need to figure out is how many milligrams/ml of Propofol are in a 1% solution. It matters not how you dilute it. The dose won’t change only the concentration will. 

So that would give me 2 mg/ml? I know that 1% is 10 mg/ml.. what's confusing me is if there would be a difference with taking 1 cc of 1% vs 5 cc of 1% but from your post, seems like there is no difference as to how much you take out since 1% will be constant from the get go.

Share this post


Link to post
Share on other sites

4 Followers; 17,976 Visitors; 2,757 Posts

Show me how you got 2mg/ml so I can see where you’re getting hung up. 

Share this post


Link to post
Share on other sites

6,191 Visitors; 149 Posts

1 hour ago, Wuzzie said:

Show me how you got 2mg/ml so I can see where you’re getting hung up. 

Well initially I got 5 mg/ml (5 cc of 1% prop in 5 cc lido)...but may have misinterpreted your post and so my other answer concluded to 2 mg/ml (1 cc 1% prop divided by 5 cc lido = 2 mg/ml)

Share this post


Link to post
Share on other sites

1 Follower; 47,450 Visitors; 2,165 Posts

One of our members, a retired pharmacist, has written a textbook (Pharmacy Calculations for Pharmacy Technicians) that he has made available.  Although written for pharmacy technicians most of the material is applicable to nursing as well.  If you are not familiar with dimensional analysis you might find it helpful.
 

Share this post


Link to post
Share on other sites
advertisement

MunoRN has 10 years experience and works as a Critical Care.

63,669 Visitors; 6,068 Posts

You might be overthinking this.  You know you've got 5ml of 10mg/ml Propofol, and you know your final volume.  So how many mgs of Propofol are in that final volume?

Share this post


Link to post
Share on other sites

1,607 Visitors; 115 Posts

It looks like you have 50 mg in 10 mL = 5mg/mL of propofol in the mixture.

Share this post


Link to post
Share on other sites
  • Recently Browsing 0 members

    No registered users viewing this page.

×