I had a patient (who had Congestive Heart Failure, pleural effusion, diabetes, and a history of hypertension, and emphysema)... my instructor claims that those medical conditions will make insulin (subcutaneously) take a much, much quicker effect (so if the book says that the onset is 15 min, in his case it will be 3-5 min)... Can someone please explain how this would happen and why? What do you think about this??