Re: Infection control problems using single use vials? When in doubt, and the manufacturer can't tell you, look for research instead of forum opinions. The very first google page yielded all this:
"CONCLUSIONS. This study shows the lack of necessity of any disinfection procedure on the rubber stopper of single-dose vials and the efficacy of alcohol only for disinfecting the stopper of multiple-dose vials."
Defining unnecessary disinfection procedures for single-dose and multiple-dose vials. Am J Crit Care. 1994 Nov;3(6):448-51.
from
http://www.ncbi.nlm.nih.gov/pubmed/7...ubmed_RVDocSum And just for aiding your argument, articles about whether to disinfect multi-dose vials:
" At our hospital, we cultured 1,223 weekly samples from 863 MDV in-use over a three-month period. Medications included xylocaine, insulin, heparin, immunizations, and miscellaneous agents. None of the samples was culture-positive. "
http://www.ncbi.nlm.nih.gov/pubmed/6562087
"Our results showed that bacterial contamination of multidose injectable vials was not a significant hazard"
http://jcm.asm.org/cgi/reprint/17/2/377.pdf
"The authors collected weekly samples from 351 in-use MDV for seven consecutive weeks ... No vial yielded bacteria."
http://www.ncbi.nlm.nih.gov/pubmed/3994029?ordinalpos=1&itool=EntrezSystem2.PEntrez.P ubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pu bmed_Discovery_RA&linkpos=4&log$=relatedarticles&l ogdbfrom=pubmed
Counterviews:
"In light of a possible high risk in this [1300-bed] hospital of about 1 contaminated MDV per day, and in view of many reported outbreaks induced by contaminated MDVs, the following infection control measures were encouraged: alcohol hand hygiene, the disinfection of gums [rubber], ..."
Am J Infect Control. 2004 Feb;32(1):12-6.
"A proportion of 4% of [96] vials was not sterile [after 4 months]."
Wien Med Wochenschr. 2007;157(15-16):398-401.
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