IVPB Zofran? - page 2
So, I was caring for an end-stage cancer patient with extreme nausea. She was on 8 mg PO Zofran q 4 hours. She was only getting partial relief from the po zofran and was allergic to phenergan, also had rectal compazine but... Read More
- 0Jan 15, '12 by Perpetual StudentI would have no concern about giving 8 mg of ondansetron IV. As a matter of fact, I effectively do it all the time when a patient receives 4 mg at the end of the surgery and 15 min later is c/o nausea and I give another 4 mg followed by perhaps 10 mg of metoclopramide. The big boogeyman with ondansetron is QT prolongation, so having a baseline ECG that shows a normal QT interval would be nice before such hefty doses. Slapping a tele box on might not hurt either, but I wouldn't say it's necessary, especially in the patient described in the OP.
Ironically, the same supervisor that was so worried we were going to overdose the patient with Zofran is now saying there is no reason we shouldn't be able to give Fentanyl IVP which I think is a lot more dangerous.