32 years ago in NICU, we manually primed tubing before connecting to stringe pump, but things may have changed as awareness of potential problems become evident. All I can say is, remember every machine is just a machine, keep an Eagle eye on all equipment used in the care of your neonate patient to make sure they are working with precision. Don't trust machines in the care of your neonate patient. Example: I had a neonate on a ventilator who was not responding well, O2 sats were staying low, lungs were clear, tube was in place. As we moved the neonate to the area to be placed on ECMO, we were manuallly bagging him, sats rose and he was well. The ventilator was not functioning properly!!! What an eye opener that was. I never fully trusted the machines again.