Quote from GilaRN
You pretty much answered your own question. It is reasonable to consider an agent with less beta effects. However, the real question being, what is the cause of the hypotension? I would hope fluid volume and preload problems would have been considered?
Gosh, with all those pressors going, one would certainly hope so, LOL... Seriously, going from Levophed down to Neosynephrine may mildly save some cardiac work, but one has to consider that Neo isn't as powerful a pressor as Levo; so you're going two steps forward and one step back, IMHO.
The other question on my mind would be that someone with a augmented systolic of 40's doesn't sound too clinically hopeful. There wasn't any indication in the OP of what counterpulsation ratio was being used so I'm assuming it's already 1:1 since the pressure is so low. Since the stented lesions were in the Left Circumflex Artery (LCX) the other nagging question is why the severe impact on overall cardiac function. A possible explanation may be that it was LCX dominant heart to begin with, such that occlusion of the LCX impacted a much greater percentage of the left ventricle (LV). I'm guessing that this was an Acute Myocardial Infarction (AMI) with subsequent cardiogenic shock. We also don't know if there was any other pre-existing myocardial pathology; ie. this may have been a repeat event.
Given that they've already stented the patient and resolved the ischemia issue; it may be worthwhile to consider Dobutamine despite the increased cardiac oxygen consumption and work. I've been told that sometimes after surgery or cardiac arrest, a heart loses its ability to fully contract secondary to myocardial stunning; temporary use of a positive inotrope like Dobutamine may force the heart muscle into more effective action. Failing that, surgical implantation of a Ventricular Assist Device (VAD) may be another medical consideration worth discussion. At any rate, unfortunately, the clinical status described here is, like the OP noted (...circling the drain)
Oh, ...and a hearty welcome to the new member; glad to have ya here!