Spiderella 138 Posts Specializes in Trauma ICU, MICU,Tele. PCU, IMC. Has 9 years experience. Apr 17, 2010 FYI: There is no blood test that can tell if someone is having a sickle cell crises. The lab work that is checked, is their H&H levels to see if we need a blood transfusion since we are usually anemic. Their Coags are checked to make sure they aren't about to throw clots. Another thing is the retic counts to see what percentage of blood cells are sickled, but this does not define a crises. You can't tell someone is in crises from lab work. So if someone comes to you in sickle cell crises, contesting this because of their 'labs' doesn't make sense and is not true. To keep it simple, if someone tells you they are in pain...believe them.