Seen Tendon Rupture From Cipro?

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Specializes in Psych.

Just wondering if anyone has seen spontaneous tendon rupture in from cipro suspension, or a feeding tube completely blocked by the suspension?

Had an order to administer cipro suspension via G-tube and the pharmacy warning on the box said not to administer via feeding tubes. The rationale seems to be the case studies whereby several feeding feeding tubes were blocked and/or the absorption is variable

due to the flushes and feedings.

Apparently, there were cases of spontaneous tendon rupture up to 6 six weeks after the cipro was stopped in peds patients.

The pt in question is an adolescent who will have foot surgery in the next few weeks.

What precautions, if any, would you take? Thank you!

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Have seen it from Levaquin- similar drug.

Apparently, the FDA has seen it.

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Specializes in ICU, LTACH, Internal Medicine.

It happens with all quinolones, and not only with teen-aged patients. Not a common thing, but a known complication, which cannot be predicted or prevented. Cipro is just most commonly ordered for outpatients, therefore there are more cases associated with it.

Administration through PEG is entirely different issue, though. There are some meds which should not be ordered in this situation.Tamsulosin is another common one just not destined for PEGs, although large volumes, constant agitation while injecting and at least 60 cc flush usually solve the problem.

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Specializes in Psych.

Thank you so much for your responses! Would you get an order clarification from the doctor that he/she wanted via g-tube if it arrived from the pharmacy with the label advising against it, and then chart that you confirmed the doctor wanted via that route?

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