I've been a clinical research nurse (oncology as well) for just over 2 years, and I love it. Don't get me wrong - there's still frustration, occasional boredom, sometimes going from bored to frantic very quickly. I don't miss 12 hour shifts at the bedside! I have a huge amount of autonomy in my day-to-day work, and a great collaborative relationship with our providers. Some of our studies follow up for 10 years, so you still get to develop a good rapport with patients.
During a typical week I will screen about a hundred patients (some are super quick, some take a lot of time), attend 1-2 tumor conferences, attend 2-3 patient visits (make sure the doctor documents the necessary assessments, collect questionnaires, maybe collect labs, process the blood & ship it out, then complete data entry for the visit), enroll 2 patients on an easy radiology study, and spend a lot of time tracking patients through our EMR and phone calls. On top of that there are webinars/training/reading for new studies or study updates, audits, and other admin-type tasks. Sometimes I have to help patients with insurance, appointment, or transportation issues.
I do feel like I've lost a lot of my "bedside" skills, but honestly, I could pick those up again pretty quickly if I needed to. I draw blood for labs, but that's about it. I do a lot of focused assessments & medical history review, but I don't do full head to toe assessments anymore. Sometimes I do neurocognitive testing or other specialty assessments. I also feel like I have learned SO much about disease progression and treatment compared to bedside nursing.
My site isn't grant funded, but with research there is always pressure to enroll. 2 patients per month is a reasonable expectation, depending on the studies & patient population you have available. My site has 5 full time coordinators, and our enrollment goal is 30 per year. Some studies might only enroll 1-2 patients per year, and then we have some simple studies that enroll several per week.