Short answer: definitely no regrets.
My last job was as a float nurse (both direct patient care and case management) for an outpatient clinic group. 2 years ago I started a job as an outpatient case manager & manager for medicaid members w/behavioral health issues. My job was originally in the office, but due to COVID I have been 95% remote since late March. I love it. I am an introvert though, like to manage my own time/plan my day, have my own space, minimal interruptions. If you are very social/extroverted it may be difficult.
Cons: in the time of covid at least, you don't leave your house much.
Absolutely no regrets, im hoping to stay mostly remote in the future