klone replied to Corey Narry's topic in Critical Care
Remdesivir - given IV because it is poorly absorbed orally. As such, infants are unlikely to absorb clinically significant amounts of the drug from milk. In addition, newborn infants have directly...
klone replied to Corey Narry's topic in Critical Care
Fentanyl is also rated L2. It has low oral bioavailability, which means that very little of what is in the milk will actually get into the infant’s bloodstream. According to Hale, “The relatively...
klone replied to Corey Narry's topic in Critical Care
Okay, reading about Propofol (continuous infusion). It’s categorized as L2 (probably compatible). Only very low concentrations are found in breastmilk, and it is rapidly cleared from neonatal...
klone replied to Corey Narry's topic in Critical Care
Yes, I understand these are IV meds. My point regarding oral bioavailability is how bioavailable are these IV meds when ingested orally (by the infant). Many IV meds will pass right through the system...
klone replied to Corey Narry's topic in Critical Care
One needs to keep in mind that the amount that goes through to the breastmilk is a very tiny percentage. Also, there is the question of oral bioavailability, as well as protein binding. That’s why...
klone replied to Corey Narry's topic in Critical Care
Are you familiar with Thomas Hale’s “Medications and Mother’s Milk”? That’s the text that we rely on to determine if a medication is okay with breastfeeding.
As far as I know,...
klone replied to Corey Narry's topic in Critical Care
You’re right - It used to be thought that entry of fetal cells into maternal circulation is what caused AFE, but now we know that fetal cells are present in maternal circulation a good percentage of...
klone replied to Corey Narry's topic in Critical Care
Here's a great presentation on the use of A-OK protocol for AFE. Sadly, many nurses and even OB providers are unfamiliar with this treatment protocol....
klone replied to Corey Narry's topic in Critical Care
Okay, I know labor dude and I are on the same page. I'm going to diagnose this patient with an AFE (amniotic fluid embolism). Even though it's rare, the hallmark sign that that is what is going on is...
klone replied to Corey Narry's topic in Critical Care
No - we have women who have PPROMed at 20 weeks hang out in antepartum for months. We watch closely for infection and fetal wellbeing. Assuming both of those things are fine, we try to keep them...
klone replied to Corey Narry's topic in Critical Care
Not typically, unless she starts to show signs of infection or her GBS comes back +. Latency abx for PPROM (preterm premature rupture of membranes) is generally only recommended <34 weeks...
klone replied to Corey Narry's topic in Critical Care
1: Fever, localized abdominal pain, elevated WBCs, other signs of sepsis such as change in vital signs, fluid that changes from clear to green, yellow, or bloody. Also concerning would be a category...
Oh mah gawd
What's weird is NONE of those other articles said anything about groups of people cheering over the death of someone.
I guess anything's possible when you make ***