I want your take on the recent oncology drug shortage we are experiencing now. Drugs like cytarabine, leucovorin, thiotepa, etoposide, bleomycin, doxorubicin, and cisplatin. During our last GI tumor board meeting, I heard about clinics in the midwest complaining about shortage of 5FU. Im concern about inadequate substitutions, inadequate alternatives and rationing. Its hard for me to explain to a patient that I can not give them X drug because they are not enrolled in a clinical trial or that they are not being treated adjuvantly. It distresses the patients and it worries me.Whats your take on this situation?