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Meperidine vs Morphine for Pain, Acute pancreatitis

Med-Surg   (11,142 Views 7 Comments)
by JP Salting JP Salting (New Member) New Member

517 Profile Views; 1 Post

What is the drug of choice for patients with acute pancreatitis in pain? This has been asked in our practice test and I chose Morphine over Meperidine. Some professionals say it's Meperidine. Which is which?

Edited by JP Salting

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mamiekay specializes in Med/Surg GI/GU/GYN.

47 Posts; 2,193 Profile Views

We use either morphine or hydromorphone for acute pancreatitis. In our facility, meperidine is rarely used on a med/surg unit. The following article explains why meperidine is not the drug of choice. http://www2.kumc.edu/druginfo/pharmkey/Meperidine%20pharmacy%20key.htm It's from 2002, but it's the most current I could find.

Now, anyone who's ever been a nursing student knows that tests don't always represent the real world. Good luck!!!

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tewdles has 31 years experience as a RN and specializes in PICU, NICU, L&D, Public Health, Hospice.

3,156 Posts; 30,759 Profile Views

I personally think meperidine is not the best pain reliever and would always prefer to give morphine...but then again, I am not the prescriber.

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K+MgSO4 has 12 years experience as a BSN and specializes in Surgical, quality,management.

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pethidine(international generic name for meperidine) has some nasty side effects seizures, deliurm etc. Morphine is the gold standard. Pethidine is faster acting but shorter in duration. It has pretty much fallen out of favour in my hospital where we have one of the top hepato-biliary consultants in Australia.

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iluvivt has 32 years experience as a BSN, RN and specializes in Infusion Nursing, Home Health Infusion.

2,726 Posts; 24,592 Profile Views

Somewhere in the back of my brain I am remembering that Meperidine specifically relaxes the sphincter (what spnchter you ask...I think its Oddi but I would have to look it up ) and relaxed sphincter = less pain. I will see if I can find the info tomorrow.too tired tonoc.

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ZippyGBR is a BSN, RN and specializes in Spinal Cord injuries, Emergency+EMS.

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pethidine(international generic name for meperidine) has some nasty side effects seizures, deliurm etc. Morphine is the gold standard. Pethidine is faster acting but shorter in duration. It has pretty much fallen out of favour in my hospital where we have one of the top hepato-biliary consultants in Australia.

rarely see Pethidine in the Uk any more either, due to the side effect profile, the fact that 100mg of diclofenac PR is as or more effective for renal colic and the madwives rules medicine act exemption now includes morphine ...

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