Updated: Published
Members are discussing the compatibility of medications with different saline solutions, specifically normal saline (NS) and half normal saline (1/2 NS). Some members believe that if a medication is compatible with NS, it will also be compatible with 1/2 NS due to the similar sodium and chloride levels. Others suggest calling the pharmacy to verify compatibility, while some mention specific examples like IV Dilantin being compatible with both NS and 1/2 NS. Additionally, resources such as drug compatibility charts are shared to provide more information on the topic.
Maybe this is a dumb question(don't you love posts that start this way?) but if a med is compatible with NS, do you assume it is also compatible with 1/2 normal saline? I'm kind of a "by the book" girl and don't hang things together that aren't tested. But my coworker says if it's compatible with NS, it would also be with 1/2NS as it's just a different concentration. What say you?
wtbcrna, MSN, DNP, CRNA
5,128 Posts
These links may help. There are several variables to consider including dilutent amount, pH, and infusion time.
These links explain the reasons why some medications are compatible with certain solutions and medications.
To mix or not to mix â€" compatibilities of parenteral drug solutions - Australian Prescriber
http://www.medscape.com/viewarticle/590261_3
Drug compatibility chart.
http://www.pharmacypracticenews.com/download/IV_drugs_ppn0911_WM.pdf
Drug-solution compatibility chart.
https://www.scribd.com/doc/24528278/IV-medication-Solution-Compatibility-Chart-for-nurses