Invega Sustenna Initial loading and booster

[123_y_321]

So, I was informed that I have to give Invega Sustenna Initial loading and booster in the Deltoid only. Does any nurses out there know the rational why?

[vintagemother, BSN, CNA, LVN, RN]

I don't know. But the information that comes with the dose specifies this.

http://www.drugs.com/dosage/invega-sustenna.html

http://reference.medscape.com/drug/invega-sustenna-paliperidone-342992#0

[123_y_321]

Thanks vintagemother. the fact the I don't know why; irritated me so bad hahahha

[Altra, BSN, RN]

Monthly maintenance doses may be given in either the deltoid or gluteal muscle, per the information contained in the reference supplied by the previous poster.

[123_y_321]

Thanks Altra for a fast reply. Still, it does not explain why we give the first 2 doses in the Deltoid.

[Anonymous865]

So, I was informed that I have to give Invega Sustenna Initial loading and booster in the Deltoid only. Does any nurses out there know the rational why?

This is from the prescribing info:

"Following intramuscular injection of single doses (39mg - 234mg) in the deltoid muscle, on average, a 28% higher Cmax was observed compared with injection in the gluteal muscle. The two initial deltoid intramuscular injections of 234 mg on day 1 and 156 mg on day 8 help attain therapeutic concentrations rapidly"

Go to

http://www.janssencns.com/invegasustenna/about

click on the link Please see the full prescribing information that is buried in the text. That will download a PDF that contains this information on page 39