Please also remember the limitations of research.
In regards to meds, frequently are researched with limits on other meds (pt taking the research med and no more than two other meds), or limitations regarding gender or pt health status. Then when the drug is introduced to the general population, it fails to show the same results or worse, does harm (How many pts are on no more than three meds, are of the test group type, or have the same co-morbidity status?). Research is not always the be all and end all for facts.
Personal experience: I had a resistant respiratory infection (about 10 years ago). My physician prescribed me a brand new drug, Omniflox (not sure of the spelling
). Within about 2 weeks, I turned a wretched shade of yellow - lab draws showed liver problems. Omniflox (?) was pulled from the market shortly thereafter, due to some deathes. Yet, research had shown it to be a safe drug.
Thalidomide passed a number of animal safety tests, but its use in humans proved diasterous, yet may still prove useful for myeloma.
Propulsid was in use for years, before many problems were found with it.
Xanax was at one time thought to be benign and nonaddictive.
Research is a wonderful tool but needs to be tempered with caution and common sense.