I'm currently an Air Force nurse with 15 years in. If you're interested-go for it. I joined with no intention of making it a career, just wanted to do something different...now I'm five years away from a retirement check!
I have loved the life style and respect I get as an officer. The best thing about AF nursing is that you can't stagnant and you won't be a staff nurse for the next 20 years.
Re: going places on your time off-yes traveling 800 miles on a four day weekend is do-able, obviously you plan on flying. Just keep in mind that flights are late, cancelled and the weather can get bad...although you can always call your supervisor and explain your situation, I don't advise it. You'll more than likely come back to a letter of counseling.
BUT don't let this stop you from joining-it wouldn't be any different in the civilian world.
e-mail me if you have any more questions