Ducks, Chickens, Bits of DNA, and Warning Signals of Flu Infection

[indigo girl]

I'm an epidemiologist, not an immunologist or a virologist but I like reading immunology and virology. It's interesting, in some ways for me it's more interesting than reading epidemiology. In an epidemiological paper I can see pretty quickly where things are going (or going wrong) and there isn't much mystery. But the sheer number of moving parts in a cellular system is amazing and confounding. Navigating through the myriad bits and pieces that appear every week in the scientific literature is tough for experts and even tougher for the rest of us who aren't experts. Vincent Racaniello over at Virology Blog is a great source of information and I read him in an effort not to fall too far behind and help me understand new papers as they come out. One appeared the other day in the Proceedings of the National Academy of Sciences (PNAS; hat tip reader hjmler) that was billed in the LA Times as showing that a bit of duck DNA protects that animal from the lethal effects of the flu virus. Well, maybe. There was the ever-present qualifier "might" that seems to appear in many "news" articles based on press releases. To me it's a signal that a reporter or university media flack is trying to get a scientist to say more than they would to other scientists, and that's the case here -- "Bit of duck DNA might protect poultry from flu, scientists say":

In a study published online March 22 in Proceedings of the National Academy of Sciences, researchers said they've found that a key influenza-fighting gene in wild ducks is absent in chickens. Genetically modifying chickens with a copy of that gene might render them resistant to influenza A, the most common form of flu infecting humans.

"If we could shut down influenza (in chickens), it would be of great commercial interest," said lead author Katharine E. Magor, a comparative immunologist at the University of Alberta in Edmonton. (Amina Khan, LA Times via PhysOrg.com)

More at: http://scienceblogs.com/effectmeasure/2010/03/ducks_chickens_bits_of_dna_and.php

[lamazeteacher]

The finding by the National Academy of Science, of anti A in wild ducks, and not in chickens is extremely important economically and epidemiologically. What a find!

Indigo girl thank you so much for sharing that.

[oramar]

I think it is darn interesting also.